First episode psychosis: The relation between symptoms, initial treatment, and clinical response
Loading...
Files
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Turkish Association of Nervous and Mental Health
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Objective: It was aimed to explore the relationship of clinical psychopathology and treatment response with "duration of untreated psychosis" (DUP) and "duration of untreated illness"(DUI) in 15-20 years old (mean age: 17,34 ± 1.69) inpatients in Turkey. Method: Mood disorders with psyhotic features were grouped as affective psychoses (18 patients, mean age: 17,28 ± 1,75); schizophrenia, schizophreniform disorder and other psychotic disorders were grouped as non-affective psychoses (25 patients, mean age: 17,38 ± 1,68). 43 patiens (11 females, 32 males) were evaluated for acute treatment response with Positive and Negative Sydrome Scale - PANSS and Clinical Global Impressions Scale -CGI. Results: Mean DUP was determined as 6,5 ± 12,4 weeks, mean DUI was determined as 37,8 ± 49,8 weeks. For the affective psychosis (AP) group; mean DUP was 1,9 ± 1,2 weeks, mean DUI was 24,6 ± 37,1 weeks, for the non-affective psychosis (NAP) group; mean DUP was 9,8 ± 15,5 weeks, mean DUI was 47,3 ± 55,9 weeks. Treatment response was better for the non-affective psychosis group and for the patients who had earlier access to treatment. Shorter DUP and DUI was related with better PANSS negative symptom severity at the time of the discharge. Conclusion: Better treatment response related with shorter DUP and DUI reveals the significance of early treatment for the disease prognosis.
Description
PubMed ID: 26111283
Keywords
Adolescent psychiatry; Age of onset; Prodromal symptoms; Psychopharmacology; Psychotic disorders
Journal or Series
Turk Psikiyatri Dergisi
WoS Q Value
Scopus Q Value
Q3
Volume
26
Issue
2
