Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study

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dc.authorid
dc.contributor.authorÇelik, Önder
dc.contributor.authorHatırnaz, Şafak
dc.contributor.authorErşahin, Aynur
dc.contributor.authorBaşbuğ, Alper
dc.contributor.authorYıldırım, Gonca Yetkin
dc.contributor.authorÖzener, Vahit
dc.contributor.authorÜnlü, Cihat
dc.date.accessioned2021-12-01T18:23:57Z
dc.date.available2021-12-01T18:23:57Z
dc.date.issued2020
dc.department[Belirlenecek]en_US
dc.description.abstractObjective: To investigate whether prior testis magnetic resonance spectroscopy predicts the success or failure of micro-dissection testicularsperm extraction (micro-TESE) in patients with non-obstructive azoospermia (NOA).Material and Methods: Nine men with NOA who were scheduled for micro-TESE for the first time, 9 NOA men with a history of previousmicro-TESE and 5 fertile men were enrolled. All NOA patients and fertile controls underwent testis spectroscopy. A multi-voxel spectroscopysequence was used. Testicular signals of choline (Cho), creatine (Cr), myo-inositol (MI), lactate, and lipids were analyzed quantitatively andcompared with the results of the micro-TESEs.Results: The most prominent peaks were Cho and Cr in the fertile controls and NOA subjects with positive sperm retrieval in the micro-TESE. Ahigh Cho peak was detected in 87% of the NOA men with positive sperm retrieval. NOA men without sperm at the previous micro-TESE showeda marked decrease in Cho and Cr signals. For positive sperm retrieval in micro-TESE, the cut-off value of Cho was 1.46 ppm, the cut-off value ofCr was 1.43 ppm, and the cut-off value of MI was 0.79 ppm.Conclusion: Testis spectroscopy can be used as a non-invasive screening method to predict the success or failure of micro-TESE. (J Turk GerGynecol Assoc 2020; 21: 70-8)en_US
dc.identifier.endpage78en_US
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.issue2en_US
dc.identifier.startpage70en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpZME9ETTNOdz09
dc.identifier.urihttps://hdl.handle.net/20.500.12684/9805
dc.identifier.volume21en_US
dc.identifier.wosWOS:000540310000002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of the Turkish-German Gynecological Associationen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keywords]en_US
dc.titleTestis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot studyen_US
dc.typeArticleen_US

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