HBSAG, ANTI-HCV, ANTI-HIV 1/2, AND SYPHILIS SEROPREVALENCE IN BLOOD DONORS IN EASTERN MARMARA REGION, TURKEY AND AN OVERVIEW OF TRANSFUSION TRANSMITTED INFECTIONS IN TURKEY

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dc.contributor.authorAltındiş, Mustafa
dc.contributor.authorKöroğlu, Mehmet
dc.contributor.authorMutlu, Birsen
dc.contributor.authorDemiray, Tayfur
dc.contributor.authorDal, Tuba
dc.contributor.authorŞahin, İdris
dc.contributor.authorÖzçelik, Ümit
dc.date.accessioned2020-05-01T12:10:18Z
dc.date.available2020-05-01T12:10:18Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionAltindis, Mustafa/0000-0003-0411-9669;en_US
dc.descriptionWOS: 000375338000011en_US
dc.description.abstractIntroduction: Blood transfusion and component therapies are life-saving medical practices. However these therapies, are not without risks and may lead to the transmission of infectious agents from donor to recipient. Screening of blood donations for infectious agents is necessary to achieve transfusion safety. The aim of the study was to determine the six-years seroprevalence of HBV (hepatitis B virus), HCV (hepatitis C virus), HIV (human immunodeficiency virus), and syphilis in blood donors and to present an overview of transfusion transmitted infections in Turkey. Material and methods: A total of 150,787 volunteer blood donors who admitted to blood centers located in Eastern Marmara Region, Turkey between January 2009 and October 2014 were included in this study. HBsAg (hepatitis B surface antigen), anti-HCV (hepatitis C virus antibody), and HIV-1/2 antibody were detected by using Chemiluminescent Microparticle Enzyme Immunoassay (CMIA) method.. Syphilis screening was performed by using VDRL (Venereal Disease Research Laboratory) test in the first three years and by CMIA-based treponemal test in the last three years. Results: Among the blood donors, 140,536 (93.2%) were male and 10,251 (6.8%) female. Out of all donors, 2,019 (1.33%) donors were positive for at least one screening test. The seroprevalence of HBV, HCV, HIV, and syphilis were 0.8 % (n=1340), 0.38% (n=578), 0,0025% (n=38) and 0,004 % (n=63), respectively. A significant decrease was observed in HBV seroprevalence by years (p <0.005) Conclusion: The risk of transfusion-transmitted infections can be decreased by effectively using questionnaires and screening tests in blood donation centers, HBV vaccination programs, and awareness-raising activities. It is necessary to use improved screening methods for detection of transfusion-transmitted infection agents.en_US
dc.identifier.endpage347en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage343en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6128
dc.identifier.volume32en_US
dc.identifier.wosWOS:000375338000011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectblood donorsen_US
dc.subjectHBsAgen_US
dc.subjectanti-HCVen_US
dc.subjectanti-HIVen_US
dc.subjectsyphilisen_US
dc.subjectTransfusionen_US
dc.titleHBSAG, ANTI-HCV, ANTI-HIV 1/2, AND SYPHILIS SEROPREVALENCE IN BLOOD DONORS IN EASTERN MARMARA REGION, TURKEY AND AN OVERVIEW OF TRANSFUSION TRANSMITTED INFECTIONS IN TURKEYen_US
dc.typeArticleen_US

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