Analysis of 3702 patients with acne vulgaris and concomitant comorbidities in Turkey: a multi-centered, prospective, controlled study

dc.authoridBAYKAL SELCUK, Leyla/0000-0001-7956-4033
dc.authorwosidDizen Namdar, Nazli/AAZ-6114-2021
dc.contributor.authorUnal, Emine
dc.contributor.authorKaradag, Ayse Serap
dc.contributor.authorAkturk, Aysun Sikar
dc.contributor.authorNamdar, Nazli Dizen
dc.contributor.authorKelekci, Kiymet Handan
dc.contributor.authorAksoy, Berna
dc.contributor.authorBalta, Ilknur
dc.date.accessioned2021-12-01T18:51:11Z
dc.date.available2021-12-01T18:51:11Z
dc.date.issued2021
dc.department[Belirlenecek]en_US
dc.description.abstractBackground Acne vulgaris is a chronic inflammatory skin disease that affects the pilosebaceous unit. Although it is considered to be a skin-limited disease, different clinical studies have recently been published in which the disease is accompanied by systemic symptoms. In this study, systemic comorbidities accompanying acne vulgaris and the relationship between existing comorbidities and disease severity are investigated. Methods This prospective multicenter study was conducted by the Turkish Society of Dermatology Acne Study Group. Twelve dermatology clinics and 14 clinicians throughout Turkey participated in the study. A structured physician-administered questionnaire was used to collect patient demographics, clinical findings, and lifestyle data. Physicians recorded each participant's medical history, including current and past comorbidities, duration of any comorbidity, smoking, and drinking. Body mass index (BMI) was calculated. Results There were 3022 patients in the adolescent acne group and 897 in the control group. The incidence of nonmigraine headache in adolescents with acne was significantly higher than in the nonacne group (P = 0.019). There were 680 patients in the postadolescent acne group and 545 in the control group. In the postadolescent group, incidence of metabolic disease was lower than the control group (P = 0.003). In the postadolescent group, premenstrual syndrome (P < 0.001) and PCOS (P = 0.007) were more common than the control group. Conclusions In this study, we observed that acne vulgaris does not cause systemic comorbidities. There is also a need for new studies involving a large number of patients to illuminate systemic diseases accompanying acne vulgaris.en_US
dc.identifier.doi10.1111/ijd.15406
dc.identifier.endpage604en_US
dc.identifier.issn0011-9059
dc.identifier.issn1365-4632
dc.identifier.issue5en_US
dc.identifier.pmid33471379en_US
dc.identifier.scopus2-s2.0-85099564273en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage597en_US
dc.identifier.urihttps://doi.org/10.1111/ijd.15406
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10977
dc.identifier.volume60en_US
dc.identifier.wosWOS:000608907500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleAnalysis of 3702 patients with acne vulgaris and concomitant comorbidities in Turkey: a multi-centered, prospective, controlled studyen_US
dc.typeArticleen_US

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