The Effect of Oral Care with Chlorhexidine, Vitamin E and Honey on Mucositis in Pediatric Intensive Care Patients: A Randomized Controlled Trial

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dc.contributor.authorŞener, Dilek Konuk
dc.contributor.authorAydın, Meryem
dc.contributor.authorCangür, Şengül
dc.contributor.authorGüven, Evren
dc.date.accessioned2020-04-30T23:33:04Z
dc.date.available2020-04-30T23:33:04Z
dc.date.issued2019
dc.departmentDÜ, Sağlık Bilimleri Fakültesi, Hemşirelik Bölümüen_US
dc.descriptionWOS: 000461967100014en_US
dc.descriptionPubMed: 30745073en_US
dc.description.abstractPurpose: This study was performed to determine the effect of oral care using chlorhexidine, vitamin E and honey on oral mucositis (OM) management in children treated in a pediatric intensive care unit (PICU). Design and methods: The study was a randomized controlled trial with a parallel design. The study sample was composed of 150 children who were treated in the PICU of a university hospital in Turkey. Children enrolled in the study were randomly divided into six groups based on the oral care solutions used (n = 25 in each group). The Demographic Information Form and the World Health Organization Oral Mucositis Index were used for data collection. Results: The mucositis indices of the children presenting with and without OM upon admission to the PICU were compared on days 1, 3, 6, 9, 12, 15, 18 and 21 and the study found that the mucositis index values of the children treated with vitamin E were significantly lower than in the other groups (p < 0.05 for each), while those of the children given chlorhexidine were significantly higher than in the other groups (p < 0.05 for each). Conclusions: At the end of the study, vitamin E was determined to be the most effective agent in OM management, followed by honey as the second most effective agent. Chlorhexidine was found to be less effective in OM management compared to the other two agents. Based on this, vitamin E is recommended for use in oral mucositis-preventive and therapeutic oral care practices. Practice implications: The results of the present study conducted with PICU patients will be useful in the administration of oral care. These findings are also important for nurses who have the responsibility of oral mucositis management. (C) 2019 Elsevier Inc. All rights reserved.en_US
dc.description.sponsorshipDuzce University Research Fund in Turkey [2015.16.01.379]en_US
dc.description.sponsorshipThis project is supported by Duzce University Research Fund in Turkey Project Number: 2015.16.01.379.en_US
dc.identifier.doi10.1016/j.pedn.2019.02.001en_US
dc.identifier.endpageE101en_US
dc.identifier.issn0882-5963
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpageE95en_US
dc.identifier.urihttps://doi.org/10.1016/j.pedn.2019.02.001
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4887
dc.identifier.volume45en_US
dc.identifier.wosWOS:000461967100014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofJournal Of Pediatric Nursing-Nursing Care Of Children & Familiesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChlorhexidineen_US
dc.subjectHoneyen_US
dc.subjectNursingen_US
dc.subjectOral careen_US
dc.subjectOral mucositisen_US
dc.subjectPediatric intensive care uniten_US
dc.subjectVitamin Een_US
dc.titleThe Effect of Oral Care with Chlorhexidine, Vitamin E and Honey on Mucositis in Pediatric Intensive Care Patients: A Randomized Controlled Trialen_US
dc.typeArticleen_US

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