Neuropsychiatric disorders and risk factors in carbon monoxide intoxication

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dc.contributor.authorKatırcı, Yavuz
dc.contributor.authorKandiş, Hayati
dc.contributor.authorAslan, Şahin
dc.contributor.authorKırpınar, İsmet
dc.date.accessioned2020-04-30T23:19:30Z
dc.date.available2020-04-30T23:19:30Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionKandis, Hayati/0000-0001-9151-6050en_US
dc.descriptionWOS: 000291038300002en_US
dc.descriptionPubMed: 21088053en_US
dc.description.abstractNeuropsychiatric sequelae may be observed in the late phases of carbon monoxide (CO) intoxication. Establishing a link between CO-related neuropsychiatric disorders and associated risk factors may decrease morbidity and mortality by means of appropriate treatment and counseling. The aim of the present study was to determine the relationship between neuropsychiatric outcomes of CO intoxication and demographic and clinical variables. Thirty patients who presented with CO intoxication and had no known neuropsychiatric disease, and 30 healthy controls were included. Physical examinations and laboratory tests were performed. Following the 1st therapy, they underwent mental and psychiatric tests 5 times (the time of discharge, during the 1st week, and during the 1st, 3rd, and 6th months). They underwent cerebral magnetic resonance imaging (MRI) at the end of the 1st month. They were evaluated by cognitive function tests at the 6th month. Lesions relevant to CO intoxication were detected in 46.7% of the patients via cranial computed tomography and in 13.3% via MRI. Evaluation of psychiatric tests revealed a clear decrease in cognitive functions, such as immediate memory, learning, reaching the criterion, spontaneous recall, attention, visual memory, and logical memory. It was found that the patients had anxiety within the 1st month, and the frequency of anxiety reached to the value of the control group by the end of the 6th month. In conclusion, we suggested that CO intoxication might lead to neuropsychiatric disorders. Our results emphasized that in addition to standard treatment, neuropsychiatric evaluation should also be performed in patients with CO intoxication.en_US
dc.identifier.doi10.1177/0748233710387632en_US
dc.identifier.endpage406en_US
dc.identifier.issn0748-2337
dc.identifier.issn1477-0393
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage397en_US
dc.identifier.urihttps://doi.org/10.1177/0748233710387632
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3776
dc.identifier.volume27en_US
dc.identifier.wosWOS:000291038300002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofToxicology And Industrial Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCO poisoningen_US
dc.subjectcognitionen_US
dc.subjectdepressionen_US
dc.subjectanxietyen_US
dc.subjectneuropsychiatric testen_US
dc.titleNeuropsychiatric disorders and risk factors in carbon monoxide intoxicationen_US
dc.typeArticleen_US

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