Accuracy of transrectal ultrasound guided prostate biopsy: Histopathological correlation to matched prostatectomy specimens

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dc.contributor.authorÇam, Kamil
dc.contributor.authorYücel, Selçuk
dc.contributor.authorTürkeri, Levent
dc.contributor.authorAkdaş, Atıf Mahmut
dc.date.accessioned2020-04-30T22:38:56Z
dc.date.available2020-04-30T22:38:56Z
dc.date.issued2002
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000176132200007en_US
dc.descriptionPubMed: 12060438en_US
dc.description.abstractBackground: The Gleason grading system is currently the world's most commonly used histological system for prostate cancer. It provides significant information about the prognosis. Therefore, Gleason score is accepted as an important factor in therapeutic decision-making for prostate cancer. This retrospective study assessed the correlation of transrectal ultrasound (TRUS) guided biopsy and radical prostatectomy specimens in terms of Gleason scores. Methods: We reviewed the records of 103 patients who underwent radical prostatectomy due to clinically localized prostate cancer. The Gleason scores of the TRUS biopsies were compared with the respective Gleason scores of surgical specimen. Results: In 28.7% of cases, the TRUS biopsy score was the same as that of the radical prostatectomy specimen. The most significant discordance was the upgrading of well-differentiated tumors after surgery in 71.7% of cases. However, in 81.8% of cases with high Gleason score on TRUS, biopsy was correlated with poorly differentiated tumor after surgery. Conclusions: Well-differentiated tumors on TRUS biopsy did not correlate with the grades of final pathology in the majority of cases; however, a high Gleason score on TRUS biopsy usually indicated a poorly differentiated tumor on prostatectomy specimen. Therefore, the treatment algorithms for particularly well-differentiated tumors should not be deduced from biopsy histology alone.en_US
dc.identifier.doi10.1046/j.1442-2042.2002.00456.xen_US
dc.identifier.endpage260en_US
dc.identifier.issn0919-8172
dc.identifier.issue5en_US
dc.identifier.startpage257en_US
dc.identifier.urihttps://doi.org/10.1046/j.1442-2042.2002.00456.x
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2529
dc.identifier.volume9en_US
dc.identifier.wosWOS:000176132200007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBlackwell Publishing Asiaen_US
dc.relation.ispartofInternational Journal Of Urologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbiopsyen_US
dc.subjectGleason scoreen_US
dc.subjectprostate canceren_US
dc.subjecttransrectal ultrasonographyen_US
dc.titleAccuracy of transrectal ultrasound guided prostate biopsy: Histopathological correlation to matched prostatectomy specimensen_US
dc.typeArticleen_US

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