Comparison of the tuberculin skin test and the quantiferon test for latent Mycobacterium tuberculosis infections in health care workers in Turkey

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dc.contributor.authorÖzdemir, Davut
dc.contributor.authorAnnakkaya, Ali Nihat
dc.contributor.authorTarhan, Gülnur
dc.contributor.authorŞencan, İrfan
dc.contributor.authorCesur, Salih
dc.contributor.authorBalbay, Öner Abidin
dc.contributor.authorGüçlü, Ertuğrul
dc.date.accessioned2020-04-30T22:41:30Z
dc.date.available2020-04-30T22:41:30Z
dc.date.issued2007
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAnnakkaya, Ali Nihat N/0000-0002-7661-8830en_US
dc.descriptionWOS: 000246892200007en_US
dc.descriptionPubMed: 17515641en_US
dc.description.abstractThe aim of this study was to compare the efficacy of the tuberculin skin test (TST) and the quantiferon test (QFT) for detecting latent tuberculosis infection (LTBI) in health care workers (HCWs). Seventy-six participants who were working in Duzce University Hospital, where tuberculosis patients were being treated, were included in the study. TST was performed according to the Mantoux technique. QFT was performed in accordance with the manufacturer's instructions. A positive TST result was defined as an induration diameter of >= 15 mm. TSTs were positive in 41 of 76 participants (53.9%) and QFT was positive in 65 of 76 participants (85.5%). There was a significant difference between the numbers of QFT-positive and TST-positive cases (P = 0.02). When the induration diameter of TST was >= 20 min, QFT positivity was 100%. Multivariate analysis revealed that there was a significant correlation between the percentage of patients with QFT positivity and the induration diameter of TST (P = 0.009). QFT thus seems to be more effective for LTBI diagnosis than TST. However, large-scale trials including quantitative measurement of QFT in subgroups taking into account the division where HCWs are employed and the different results of TST might clarify the usefulness of QFT in LTBI diagnosis.en_US
dc.identifier.endpage105en_US
dc.identifier.issn1344-6304
dc.identifier.issn1884-2836
dc.identifier.issue02.Maren_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage102en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3197
dc.identifier.volume60en_US
dc.identifier.wosWOS:000246892200007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNatl Inst Infectious Diseasesen_US
dc.relation.ispartofJapanese Journal Of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleComparison of the tuberculin skin test and the quantiferon test for latent Mycobacterium tuberculosis infections in health care workers in Turkeyen_US
dc.typeArticleen_US

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