Characteristics of Active Tuberculosis Patients Requiring Intensive Care Monitoring and Factors Affecting Mortality

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dc.contributor.authorFiliz, Koşar
dc.contributor.authorLevent, Dalar
dc.contributor.authorEmel, Eryüksel
dc.contributor.authorPelin, Uysal
dc.contributor.authorTürkay, Akbaş
dc.contributor.authorKekeçoğlu, Aybüke
dc.date.accessioned2020-04-30T22:40:41Z
dc.date.available2020-04-30T22:40:41Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000406830100007en_US
dc.descriptionPubMed: 27433176en_US
dc.description.abstractBackground: One to three percent of cases of acute tuberculosis (TB) require monitoring in the intensive care unit (ICU). The purpose of this study is to establish and determine the mortality rate and discuss the causes of high mortality in these cases, and to evaluate the clinical and laboratory findings of TB patients admitted to the pulmonary ICU. Methods: The data of patients admitted to the ICU of Yedikule Chest Diseases and Chest Surgery Education and Research Hospital due to active TB were retrospectively evaluated. Demographic characteristics, medical history, and clinical and laboratory findings were evaluated. Results: Thirty-five TB patients (27 males) with a median age 0117 years were included, of whom 20 died within 30 days (57%). The Acute Physiology and Chronic Health Evaluation 11 (APACHE II) and Sequential Organ Failure Assessment (SOFA) scores were significantly higher, and albumin and PaO2/FIO2 levels were significantly lower, and shock, multiple organ failure, the need for invasive mechanical ventilation and drug resistance were more common in the patients who died. The mortality risk was 7.58 times higher in the patients requiring invasive mechanical ventilation. The SOFA score alone was a significant risk factor affecting surviVal Conclusion: The survival rate is low in cases of tuberculosis treated in an ICU. The predictors of mortality include the requirement of invasive mechanical ventilation and multiple organ failure. :Another factor specific to rt B patients is the presence of drug resistance, which should be taken seriously in countries where there is a high incidence of the disease. Finding new variables that can be established with new prospective studies may help to decrease the high mortalit\ rate.en_US
dc.identifier.doi10.4046/trd.2016.79.3.158en_US
dc.identifier.endpage164en_US
dc.identifier.issn1738-3536
dc.identifier.issn2005-6184
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage158en_US
dc.identifier.urihttps://doi.org/10.4046/trd.2016.79.3.158
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3038
dc.identifier.volume79en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaehan Kyorhaek Hyophoe-Korean Acad Tuberculosis & Respiratory Diseasesen_US
dc.relation.ispartofTuberculosis And Respiratory Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTuberculosisen_US
dc.subjectRespiratory Insufficiencyen_US
dc.subjectCritical. Careen_US
dc.titleCharacteristics of Active Tuberculosis Patients Requiring Intensive Care Monitoring and Factors Affecting Mortalityen_US
dc.typeArticleen_US

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