The early anti-inflammatory effect of Kefir in experimental corrosive esophagitis

Basit Öğe Kaydı
dc.contributor.authorYaşar, Mehmet
dc.contributor.authorTaşkın, Ali Kemal
dc.contributor.authorKaya, Bülent
dc.contributor.authorAydın, Metin
dc.contributor.authorÖzaydın, İsmet
dc.contributor.authorİskender, Abdülkadir
dc.contributor.authorKandiş, Hayati
dc.date.accessioned2020-04-30T23:32:47Z
dc.date.available2020-04-30T23:32:47Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000329685900014en_US
dc.descriptionPubMed: 23013643en_US
dc.description.abstractAim: Corrosive esophageal burns are still an important problem. The aim of this study was to evaluate the effect of kefir in an experimental corrosive esophagitis model. MATERIAL AND METHOD: Twenty-four male wistar albino rats were used in this experimental study. The rats were randomized into three groups according to the procedure and treatment type (each group has eight rats). Group I: (Control group), Group II: (Induction of corrosive esophagitis with 5 % NaOH without any treatment) and Group III: (Corrosive esophagitis treated with kefir). The rats were sacrificed on the first and seventh days. Mediastinum and abdominal cavity of rats were explorated. Approximately 1.5 cm of esophagus was removed for histopathological examination. Inflammation, injury in the muscularis mucosa and collagen deposition were evaluated. RESULTS: Histopathological results on the first day after caustic injury; inflammation was detected in three rats in Group II and there were no inflammation in rats in Group III. This difference was statistically significant (p<0.05). Injury in muscularis mucosa was detected in three rats in Group II and in one rat in Group III. Histopathological results on the seventh days after caustic injury; Inflammation was positive in four rats in Group II and three rats in Group III. Injury in muscularis mucosa was equal in two groups (three rats each). Collagen deposition with high grade (Grade 2) was detected in two rats in Group II and in four rats in Group III (p<0.05). CONCLUSION: Kefir has anti-inflammatory effect specially in early phase of caustic injury. It has also some beneficial effect in wound healing.en_US
dc.identifier.endpage685en_US
dc.identifier.issn0003-469X
dc.identifier.issn2239-253X
dc.identifier.issue6en_US
dc.identifier.startpage681en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4818
dc.identifier.volume84en_US
dc.identifier.wosWOS:000329685900014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEdizioni Luigi Pozzien_US
dc.relation.ispartofAnnali Italiani Di Chirurgiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCaustic injuryen_US
dc.subjectCorrosive esophagitisen_US
dc.subjectKefiren_US
dc.titleThe early anti-inflammatory effect of Kefir in experimental corrosive esophagitisen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
4818.pdf
Boyut:
139.6 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu