Clinical Characteristics Predicting Mortality Risk in Hospitalized Geriatric Patients with COVID-19 Pneumonia: a Retrospective Study

Basit Öğe Kaydı
dc.authoridBalbay, Ege Güleç/0000-0002-1557-7019
dc.authorwosidBalbay, Ege Güleç/V-5497-2017
dc.contributor.authorGüleç-Balbay, Ege
dc.contributor.authorAltundal, M. M. Bekir
dc.contributor.authorKaypak, M. Kemal
dc.contributor.authorCangür, Şengül
dc.contributor.authorKaya, Sare
dc.date.accessioned2023-07-26T11:53:56Z
dc.date.available2023-07-26T11:53:56Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalıen_US
dc.departmentDÜ, Ziraat Fakültesi, Biyosistem Mühendisliği Bölümüen_US
dc.description.abstractBackground: Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute respiratory syn-drome coronavirus 2 (SARS-CoV-2). Geriatric patients with COVID-19 are more likely to progress to severe dis-ease, and they are at increased risk of hospitalization and mortality. In this study we aimed to investigate the risk factors for predicting mortality in geriatric patients with COVID 19 by reviewing the clinical data of survivors and non-survivors. Methods: This was a retrospective study of 189 geriatric patients with COVID-19 pneumonia who were hospital-ized in pulmonology clinic, in Duzce University, Medical Faculty Hospital between March 2020 and January 2021 in Turkey. Results: In the study, 60.3% (n = 114) of the patients were male and the median age was 75. 80.4% (n = 152) of the patients were discharged. The presence of cardiovascular disease, chronic renal failure, malignancy, increased number of comorbidities, complaints of anorexia, no fever, decreased oxygen saturation value, increased pulse rate, high values of maximum (max) D-dimer, aspartate aminotransferase, urea, creatinine, troponin, lactate de-hydrogenase (LDH), max LDH, ferritin and max ferritin, C-reactive protein (CRP), max CRP, procalcitonin, max procalcitonin, potassium values and low albumin values, complications as bacterial infection, cardiac disease, acute respiratory distress syndrome, liver function tests failure, arrhythmia and shock, the need for corticosteroid and pulse corticosteroid therapy increased the mortality. According to multiple logistic regression model, the de-velopment of cardiac disease, acute respiratory distress syndrome, bacterial infection, the need for pulse steroids, and the max ferritin value increased the risk of mortality by between 1.001 and 28.715 times. Conclusions: Both clinical and laboratory parameters predicting mortality in geriatric patients with COVID-19 pneumonia should be monitored very carefully. Complications that develop should be evaluated and multidisci-plinary and necessary treatments should be initiated without delay. (Clin. Lab. 2022;68:1666-1674. DOI: 10.7754/Clin.Lab.2021.211054)en_US
dc.identifier.doi10.7754/Clin.Lab.2021.211054
dc.identifier.endpage1674en_US
dc.identifier.issn1433-6510
dc.identifier.issue8en_US
dc.identifier.pmid35975503en_US
dc.identifier.scopus2-s2.0-85135963212en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1666en_US
dc.identifier.urihttps://doi.org/10.7754/Clin.Lab.2021.211054
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12661
dc.identifier.volume68en_US
dc.identifier.wosWOS:000842640800002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorGüleç-Balbay, Ege
dc.institutionauthorAltundal, M. M. Bekir
dc.institutionauthorKaypak, M. Kemal
dc.institutionauthorCangür, Şengül
dc.institutionauthorKaya, Sare
dc.language.isoenen_US
dc.publisherClin Lab Publen_US
dc.relation.ispartofClinical Laboratoryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectCovid-19; Geriatric; Mortality; Risk Factorsen_US
dc.titleClinical Characteristics Predicting Mortality Risk in Hospitalized Geriatric Patients with COVID-19 Pneumonia: a Retrospective Studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu