The Value of Fibrinogen/Albumin Ratio on Prognosis of COVID-19 Patients

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dc.contributor.authorSarıca, Elif
dc.contributor.authorKotan, Dılcan
dc.contributor.authorSayan, Saadet
dc.contributor.authorÇiçekli, Esen
dc.date.accessioned2023-04-10T20:21:00Z
dc.date.available2023-04-10T20:21:00Z
dc.date.issued2022
dc.departmentRektörlük, Rektörlüğe Bağlı Birimler, Düzce Üniversitesi Dergilerien_US
dc.description.abstractAim: Fibrinogen and albumin are proteins that play a role in inflammation. In this study, it was aimed to investigate the role of fibrinogen, albumin, and fibrinogen/albumin ratio (FAR) levels as markers of disease severity and prognosis in coronavirus disease 2019 (COVID-19) patients. Material and Methods: Seventy-one patients aged between 19 and 84 years diagnosed with COVID-19 who were hospitalized in Sakarya University Training and Research Hospital, Neurology Department between March and May 2020 were analyzed retrospectively. Fibrinogen, albumin, FAR, D-dimer, platelet, and C-reactive protein (CRP) levels of the patients were compared according to the length of hospitalization duration, survival, and clinical severity of COVID-19. Results: Twenty-eight (%39.4) of the patients were male and 43 (%60.6) were female, and the mean age was 55.7±20.7 years. There was a significant difference between the groups of COVID-19 clinical severity in terms of age, fibrinogen, albumin, FAR, D-dimer, and CRP values (all p values were <0.001). Also, significantly higher fibrinogen, FAR, D-dimer, and CRP values were found in patients hospitalized longer, while the albumin level was lower in these patients (all p values were <0.001). FAR values were higher and albumin values were lower in non-surviving patients compared to surviving patients (p=0.025 and p<0.001, respectively). Conclusion: FAR levels may be useful in predicting mortality risk in COVID-19 patients. In addition, it may be helpful and useful in determining the prognosis since it has higher levels as the severity of the disease and the length of hospital stay increase.en_US
dc.identifier.doi10.18678/dtfd.1108086
dc.identifier.endpage181en_US
dc.identifier.issn1307-671X
dc.identifier.issue2en_US
dc.identifier.startpage176en_US
dc.identifier.trdizinid1115675en_US
dc.identifier.urihttp://doi.org/10.18678/dtfd.1108086
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1115675
dc.identifier.urihttps://hdl.handle.net/20.500.12684/11514
dc.identifier.volume24en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectfibrinogenen_US
dc.subjectalbuminen_US
dc.subjectfibrinogen/albumin ratioen_US
dc.subjectCOVID-19en_US
dc.titleThe Value of Fibrinogen/Albumin Ratio on Prognosis of COVID-19 Patientsen_US
dc.typeArticleen_US

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