Association of Between Heavy Metal and Trace Element Levels in Blood and Cervical Mucus with Female Infertility

dc.contributor.authorIlgın, Halil
dc.contributor.authorHassa, Hikmet
dc.contributor.authorKarataş, Ahmet
dc.contributor.authorKahraman, Salih
dc.contributor.authorIlgın, Bade
dc.date.accessioned2020-04-30T22:39:52Z
dc.date.available2020-04-30T22:39:52Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000309698500018en_US
dc.description.abstractObjective: Infertility affects 10-15% of couples during the reproductive period. Ovulatory disorders are more common in younger women whereas unexplained infertility occurs more commonly in older women. Recently, many environmental agents, such as cigarettes, alcohol, heat, electromagnetic energy and radiation have been shown to have negative effects on the reproductive system. Environmental factors and exposure to heavy metals change fertility patterns in adults by affecting germ cell maturation, fertilization and the endocrine system. We aimed to investigate the effect of trace elements and heavy metals in blood and cervical mucus on female infertility. Material and Methods: Study was performed with 50 women: Infertile (n=35) and controls (n=15). Blood and cervical mucus samples were collected to measure Zn, Cu, Cd, and Pb levels. Results: Mean blood plasma and cervical mucus Zn, Cd, and Cu levels in the infertile group were significantly lower than those in the control group. Whole blood Pb level was higher in the infertile group compared to the control group. Although blood Cd level tended to be higher in smokers and cervical mucus Cd level tended to be lower in controls, neither of these difference were statistically significant. Condusion: Lower levels of plasma and cervical mucus Zn and Cu were thought to result from higher levels of Cd and Pb in blood and cervical mucus. Abnormal levels of heavy metals in blood and cervical mucus may have adverse effects on the female reproductive function.en_US
dc.identifier.doi10.5336/medsci.2011-26725en_US
dc.identifier.endpage1038en_US
dc.identifier.issn1300-0292
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1032en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2011-26725
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2850
dc.identifier.volume32en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherOrtadogu Ad Pres & Publ Coen_US
dc.relation.ispartofTurkiye Klinikleri Tip Bilimleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCervix mucusen_US
dc.subjectmetals, heavyen_US
dc.subjecttrace elementsen_US
dc.subjectinfertility, femaleen_US
dc.titleAssociation of Between Heavy Metal and Trace Element Levels in Blood and Cervical Mucus with Female Infertilityen_US
dc.typeArticleen_US

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