Effect of dipping status on QRS morphology in patients with hypertension

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dc.contributor.authorErden, İsmail
dc.contributor.authorErden, Emine Çakcak
dc.contributor.authorÖzhan, Hakan
dc.contributor.authorYalçın, Sübhan
dc.contributor.authorBaşar, Cengiz
dc.contributor.authorAydın, Mesut
dc.date.accessioned2020-05-01T09:11:38Z
dc.date.available2020-05-01T09:11:38Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000281909800003en_US
dc.descriptionPubMed: 20559141en_US
dc.description.abstractBackground Prolongation of the QRS complex on the surface electrocardiogram (ECG) has been shown to be predictive of cardiovascular outcomes in selected populations. A 'nondipper' blood pressure (BP) profile is currently regarded as a risk factor in its own right for cardiovascular events and target organ damage. The predictive value of ECG parameters in hypertensives with nondipper profile has not been established. Methods A total of 750 consecutive patients with hypertension who had been evaluated with ambulatory BP monitoring were screened for this study. One hundred and thirty-six patients who had fulfilled the inclusion and exclusion criteria were included in the final analysis. Dipper and nondipper patterns were detected and the maximum QRS duration (QRSd) measured on a 12-lead ECG was recorded. Results There were 70 nondipper and 66 dipper hypertensives. There was no significant difference between the two groups regarding the daytime systolic and diastolic mean BPs, number of medications taken, and the proportion of each class of antihypertensive medications. Other variables were similar between the two groups. QRSd was significantly higher in nondippers than dippers (P = 0.006). Correlation analysis revealed that the systolic BP fall at night was inversely and significantly related with QRSd (r = -0.482, P < 0.001). Regression analysis further showed that the systolic BP fall at night and age were independent correlates of QRSd. Conclusion QRSd on the standard-surface 12-lead ECG was increased in patients with nondipper pattern and furthermore the systolic BP fall at night was independent correlate of QRSd in patients with hypertension. Blood Press Monit 15:247-250 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.en_US
dc.identifier.doi10.1097/MBP.0b013e32833c8b22en_US
dc.identifier.endpage250en_US
dc.identifier.issn1359-5237
dc.identifier.issue5en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage247en_US
dc.identifier.urihttps://doi.org/10.1097/MBP.0b013e32833c8b22
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5700
dc.identifier.volume15en_US
dc.identifier.wosWOS:000281909800003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofBlood Pressure Monitoringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthypertensionen_US
dc.subjectnondipper profileen_US
dc.subjectQRS durationen_US
dc.titleEffect of dipping status on QRS morphology in patients with hypertensionen_US
dc.typeArticleen_US

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