Association of the CHA(2)DS(2)VASc Score with Acute Stent Thrombosis in Patients with an ST Elevation Myocardial Infarction Who Underwent a Primary Percutaneous Coronary Intervention

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dc.contributor.authorTanık, Veysel Ozan
dc.contributor.authorAruğaslan, Emre
dc.contributor.authorÇınar, Tufan
dc.contributor.authorKeskin, Muhammed
dc.contributor.authorKaya, Adnan
dc.contributor.authorTekkeşin, Ahmet İlker
dc.date.accessioned2020-04-30T22:39:55Z
dc.date.available2020-04-30T22:39:55Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionKeskin, Muhammed/0000-0002-4938-0097;en_US
dc.descriptionWOS: 000467682900003en_US
dc.descriptionPubMed: 30448849en_US
dc.description.abstractObjective: In this study, we aimed to determine the predictive value of the CHA(2)DS(2)VASc score for acute stent thrombosis in patients with an ST elevation myocardial infarction treated with a primary percutaneous coronary intervention (pPCI). Methods: This was a retrospective study conducted among 3,460 consecutive patients with STEMI who under-went a pPCI. The stent thrombosis was considered a definite or confirmed event in the presence of symptoms suggestive of acute coronary syndrome and angiographic confirmation of stent thrombosis based on the diagnostic guidelines of the Academic Research Consortium. The stent thrombosis was classified as acute if it developed within 24 h. Results: The mean CHA(2)DS(2)VASc score was 3.29 +/- 1.73 in the stent thrombosis group, whereas it was 2.06 +/- 1.14 in the control group (p < 0.001). In multivariable logistic regression analysis, CHA(2)DS(2)VASc scores >= 4 were independently associated with acute stent thrombosis (OR = 1.64; 95% CI 1.54-1.71, p < 0.001). In a receiver operating characteristic curve analysis, the best cut-off value for the CHA(2)DS(2)VASc score was >= 4, with 60% sensitivity and 73% specificity. Of note, patients with a CHA(2)DS(2)VASc score of 4 had a 4.3 times higher risk of acute stent thrombosis compared to those with a CHA(2)DS(2)VASc score of 1. Conclusions: The CHA(2)DS(2)VASc score may be a significant independent predictor of acute stent thrombosis in patients with STEMI treated with a pPCI. Therefore, the CHA(2)DS(2)VASc score may be used to assess the risk of acute stent thrombosis in patients with STEMI following a pPCI. (C) 2018 The Author(s) Published by S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000495526en_US
dc.identifier.endpage123en_US
dc.identifier.issn1011-7571
dc.identifier.issn1423-0151
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage115en_US
dc.identifier.urihttps://doi.org/10.1159/000495526
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2860
dc.identifier.volume28en_US
dc.identifier.wosWOS:000467682900003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles And Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCHA(2)DS(2)VASc scoreen_US
dc.subjectST elevation myocardial infarctionen_US
dc.subjectAcute stent thrombosisen_US
dc.subjectPrimary percutaneous coronary interventionen_US
dc.titleAssociation of the CHA(2)DS(2)VASc Score with Acute Stent Thrombosis in Patients with an ST Elevation Myocardial Infarction Who Underwent a Primary Percutaneous Coronary Interventionen_US
dc.typeArticleen_US

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