Evaluation of Exudative Pleural Effusions: A Multicenter, Prospective, Observational Study

Basit Öğe Kaydı
dc.authoridKoçak, Nagihan Dumuş/0000-0003-4028-2797
dc.authoridYılmaz Demirci, Nilgün/0000-0001-6160-3778
dc.authoridSöyler, Yasemin/0000-0002-0507-0767
dc.authoridBilaceroglu, Semra/0000-0002-9703-9598
dc.authoridYılmaz, Meltem/0000-0003-0314-4774
dc.authorwosidKoçak, Nagihan Dumuş/AFM-4219-2022
dc.authorwosidSarbay, İsmail/AAB-5973-2022
dc.authorwosidYılmaz Demirci, Nilgün/C-9348-2014
dc.authorwosidYılmaz, Ülkü/HKN-2974-2023
dc.authorwosidSöyler, Yasemin/AAF-8533-2021
dc.contributor.authorAk, Güntülü
dc.contributor.authorMetintas, Selma
dc.contributor.authorTaskin, Ayse Naz
dc.contributor.authorSener, Melahat Uzel
dc.contributor.authorSoyler, Yasemin
dc.contributor.authorYılmaz, Meltem
dc.contributor.authorTurna, Akif
dc.date.accessioned2023-07-26T11:51:02Z
dc.date.available2023-07-26T11:51:02Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Anabilim Dalıen_US
dc.description.abstractPurpose The aim of this study is to determine the diagnostic performances of pleural procedures in undiagnosed exudative pleural effusions and to evaluate factors suggestive of benign or malignant pleural effusions in tertiary care centers. Methods This was a multicenter prospective observational study conducted between January 1 and December 31, 2018. A total of 777 patients with undiagnosed exudative pleural effusion after the initial work-up were evaluated. The results of diagnostic procedures and the patients' diagnoses were prospectively recorded. Sensitivity, specificity, and accuracy estimates with 95% confidence intervals were used to examine the performance of pleural procedures to detect malignancy. Results The mean age +/- SD of the 777 patients was 62.0 +/- 16.0 years, and 68.3% of them were male. The most common cause was malignancy (38.3%). Lung cancer was the leading cause of malignant pleural effusions (20.2%). The diagnostic sensitivity and accuracy of cytology were 59.5% and 84.3%, respectively. The diagnostic sensitivity of image-guided pleural biopsy was 86.4%. The addition of image-guided pleural biopsy to cytology increased diagnostic sensitivity to more than 90%. Thoracoscopic biopsy provided the highest diagnostic sensitivity (94.3%). The highest diagnostic sensitivity of cytology was determined in metastatic pleural effusion from breast cancer (86.7%). Conclusion The diagnostic performance increases considerably when cytology is combined with image-guided pleural biopsy in malignant pleural effusions. However, to avoid unnecessary interventions and complications, the development of criteria to distinguish patients with benign pleural effusions is as important as the identification of patients with malignant pleural effusions.en_US
dc.description.sponsorshipTurkish Respiratory Societyen_US
dc.description.sponsorshipThe study was supported by Turkish Respiratory Society. We thank Turkish Respiratory Society Pleura Study Group and Young Academicians Group.en_US
dc.identifier.doi10.1007/s00408-022-00573-8
dc.identifier.endpage815en_US
dc.identifier.issn0341-2040
dc.identifier.issn1432-1750
dc.identifier.issue6en_US
dc.identifier.pmid36173482en_US
dc.identifier.scopus2-s2.0-85139156590en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage807en_US
dc.identifier.urihttps://doi.org/10.1007/s00408-022-00573-8
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12481
dc.identifier.volume200en_US
dc.identifier.wosWOS:000863138500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorErçelik, Merve
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofLungen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectExudative Pleural Effusion; Cytological Diagnostic Sensitivity; Image-Guided Pleural Biopsy; Malignant Pleural Effusion; Benign Pleural Effusionen_US
dc.subjectDiagnosisen_US
dc.titleEvaluation of Exudative Pleural Effusions: A Multicenter, Prospective, Observational Studyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
12481.pdf
Boyut:
827.21 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu