The benefit of expiratory-phase quantitative CT densitometry in the early diagnosis of chronic obstructive pulmonary disease

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dc.contributor.authorBeşir, Fahri Halit
dc.contributor.authorMahmutyazıcıoğlu, Kamran
dc.contributor.authorAydın, Leyla
dc.contributor.authorAltın, Remzi
dc.contributor.authorAsil, Kıyasettin
dc.contributor.authorGündoğdu, Sadi
dc.date.accessioned2020-04-30T23:32:41Z
dc.date.available2020-04-30T23:32:41Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000316061000002en_US
dc.descriptionPubMed: 22261851en_US
dc.description.abstractPURPOSE We aimed to compare the inspiratory and expiratory quantitative computed tomography (CT) densitometric data of healthy volunteers, individuals with chronic obstructive pulmonary disease (COPD) risk, and COPD patients to aid in the early diagnosis of COPD. MATERIALS AND METHODS Of the study patients, 14 were healthy volunteers (Group I), 12 were patients at risk for COPD (Group II), and 13 were COPD patients (Group III). The high-resolution CT was performed at three levels (the upper, middle, and lower parts of the lungs). All images were evaluated with a specific program for the segmentation of pulmonary parenchyma. The mean lung density (MLD) was measured, and the emphysema index (EI) was calculated using this program. RESULTS Both MLD values and calculated EI ratios showed significant differences between Groups I and III, and Groups II and III in both expiratory and inspiratory phases (P < 0.05). However, in the comparison of healthy volunteers and patients at risk for COPD (Group I and II), only expiratory-phase MLD values showed statistically significant difference (P < 0.001). CONCLUSION In patients at risk for COPD, expiratory-phase MLD measurements can be used as an early diagnostic method.en_US
dc.identifier.doi10.4261/1305-3825.DIR.4365-11.3en_US
dc.identifier.endpage254en_US
dc.identifier.issn1305-3825
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage248en_US
dc.identifier.urihttps://doi.org/10.4261/1305-3825.DIR.4365-11.3
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4788
dc.identifier.volume18en_US
dc.identifier.wosWOS:000316061000002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkish Soc Radiologyen_US
dc.relation.ispartofDiagnostic And Interventional Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchronic obstructive pulmonary disease (COPD)en_US
dc.subjectearly diagnosisen_US
dc.subjectCT densitometryen_US
dc.subjectexpiratory phaseen_US
dc.titleThe benefit of expiratory-phase quantitative CT densitometry in the early diagnosis of chronic obstructive pulmonary diseaseen_US
dc.typeArticleen_US

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