Changes in the Anterior Segment and Dry Eye Parameters of People Using Oral Tetracycline

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dc.contributor.authorEski, Mehmet Tahir
dc.contributor.authorTeberik, Kuddusi
dc.contributor.authorSezer, Taha
dc.date.accessioned2025-03-24T19:48:33Z
dc.date.available2025-03-24T19:48:33Z
dc.date.issued2023
dc.departmentDüzce Üniversitesi
dc.description.abstractAim: The purpose of the study is to evaluate the effect of anti-inflammatory efficiency of tetracycline on dry eye and anterior segment parameters. Material and Methods: This prospective study was conducted with 61 people who had been using tetracycline for the past 2 months. Each participant went through a detailed ophthalmological examination where intraocular pressure (IOP), central cornea thickness (CCT), K1 and K2 from keratometry measurements, anterior chamber depth (ACD), axial length (AXL), tear breakup time test (BUT), lissamin green staining (LG), Schirmer’s tear test-1 (ST) and ocular surface disease index (OSDI) score were evaluated. Measurements of the patients who would be using a daily dose of 100 mg doxycycline for 2 months were done prior to the medication as well as 1 month and 2 months after the medication. 3 data sets of the participants were compared at the end of 2 months. Results: When results were compared, it was found that ST and LG parameters gradually increased in the first and second months and this increase was statistically significant (p<0.001 and p=0.018, respectively). On the other hand, BUT and OSDI scores decreased over time but it was not statistically significant. There were no statistically significant differences in terms of other parameters either (p>0.05). When female and male participants were compared in terms of BUT, it was found that the decrease in females at the second month was higher and this was statistically significant (p=0.01). Conclusion: t was concluded that the young individuals using tetracycline displayed an early stage of improvement in dry eye parameters.
dc.identifier.doi10.37990/medr.1226595
dc.identifier.endpage13
dc.identifier.issn2687-4555
dc.identifier.issue2
dc.identifier.startpage309
dc.identifier.urihttps://doi.org/10.37990/medr.1226595
dc.identifier.urihttps://hdl.handle.net/20.500.12684/19049
dc.identifier.volume5
dc.language.isoen
dc.publisherTıbbi Kayıtlar Derneği
dc.relation.ispartofMedical Records
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250324
dc.subjectDry eye|tetracycline|anterior segment|Dry eye|tetracycline|anterior segment
dc.titleChanges in the Anterior Segment and Dry Eye Parameters of People Using Oral Tetracycline
dc.typeArticle

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