Polymorphisms of kappa-casein gene and their effects on milk production traits in Holstein, Jersey and Brown Swiss cattle

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dc.contributor.authorGürses, Murad
dc.contributor.authorYüce, Hüseyin
dc.contributor.authorEtem, Ebru Önalan
dc.contributor.authorPatir, Bahri
dc.date.accessioned2020-04-30T23:21:05Z
dc.date.available2020-04-30T23:21:05Z
dc.date.issued2018
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptiononalan, ebru/0000-0001-9968-8201en_US
dc.descriptionWOS: 000428836700002en_US
dc.description.abstractThe objectives of this study were to detect kappa-casein (kappa-CN, CSN3, CASK) gene polymorphisms and to investigate the association between the kappa-CNgene polymorphisms and milk yield and composition in cattle. For this purpose, a total of 365 blood and milk samples were collected from Holstein, Jersey and Brown Swiss cows. Polymorphisms of kappa-CN gene were detected by the PCR and restriction fragment length polymorphism. A776-bp fragment of exon IV was amplified by PCR and digested with HindIII and HaeIII restriction endonuclease to distinguish allele A, B and E. The analysis of associations between kappa-CN genotypes and milk yield and composition were conducted with the use of the general linear model procedure. As a result, allele frequencies were detected as 0.736, 0.357, 0.308 for A allele, 0.186, 0.643, 0.692 for B allele in Holstein, Brown Swiss and Jersey breeds, respectively, and 0.079 for E allele in Holstein. This study also demonstrated the presence of Eallele in Turkish Holstein. Although kappa-CN genotypes were associated with protein and solids-not-fat content of milk in Hostein and Brown Swiss, they were associated with milk fat content in Jerseys (P < 0.05).en_US
dc.description.sponsorshipScientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TOVAG-107O612]en_US
dc.description.sponsorshipThe authors gratefully acknowledge the financial support from The Scientific and Technological Research Council of Turkey (Project No: TOVAG-107O612).en_US
dc.identifier.doi10.1071/AN15131en_US
dc.identifier.endpage784en_US
dc.identifier.issn1836-0939
dc.identifier.issn1836-5787
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage778en_US
dc.identifier.urihttps://doi.org/10.1071/AN15131
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4133
dc.identifier.volume58en_US
dc.identifier.wosWOS:000428836700002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCsiro Publishingen_US
dc.relation.ispartofAnimal Production Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBovine CSN3en_US
dc.subjectgenetic polymorphismen_US
dc.subjectmilk yield and compositionen_US
dc.subjectPCR-RFLPen_US
dc.titlePolymorphisms of kappa-casein gene and their effects on milk production traits in Holstein, Jersey and Brown Swiss cattleen_US
dc.typeArticleen_US

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