Analysis and evaluation of quality parameters of commercial propolis products using a new high Performance Liquid Chromatography (HPLC) method and Comparison of antimicrobial properties

Basit Öğe Kaydı
dc.authoridugras, halil ibrahim/0000-0002-1633-967Xen_US
dc.authoridugras, serpil/0000-0002-1867-5781en_US
dc.authoridUSTA, MEHTAP/0000-0001-7656-5655en_US
dc.authorscopusid57200180817en_US
dc.authorscopusid54397548800en_US
dc.authorscopusid58945428600en_US
dc.authorscopusid57224512576en_US
dc.authorscopusid6603474174en_US
dc.authorwosidugras, halil ibrahim/KSM-2767-2024en_US
dc.authorwosidugras, serpil/KSM-3256-2024en_US
dc.contributor.authorKaragul, Bora
dc.contributor.authorUgras, Serpil
dc.contributor.authorKaragul, Pinar
dc.contributor.authorUsta, Mehtap
dc.contributor.authorUgras, Brahim
dc.date.accessioned2024-08-23T16:04:41Z
dc.date.available2024-08-23T16:04:41Z
dc.date.issued2024en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractPropolis, which has an important place in functional foods, is a natural bee product with high biological active value and is consumed in different formulations and packages worldwide. Thanks to the active compounds it contains, propolis shows biological properties such as antibacterial, antifungal, antiviral, antiprotozoal, antitumoral, antiulcer and anti-inflammatory. However, it is seen that propolis supplements are prepared unconsciously in the market. Such commercial products need to be standardized. Within the scope of this study, characteristic compounds of Turkish propolis were initially determined with support from the literature. Subsequently, bioactive components of 23 commercial propolis products were analyzed using the new HPLC method. Then, the flavonoid content and antimicrobial activity of the samples were determined. According to the results of these analyses, the amounts of Caffeic Acid (2,16-1620,57 ppm, Quercetin (0,19-203,99 ppm), Apigenin (0,30-319,08 ppm), Kaempferol (0,56-251,15 ppm), Chrysin (3,97-2830,93 ppm), and Caffeic Acid Phenethyl Ester (13,08-9666,48 ppm) were found to be quite different. The highest flavonoid content was measured as P2: 20847,43 mg/L and the lowest was 00003,10 mg/L in sample P13. Samples prepared for children were found to be highly diluted in terms of content. Again, it was determined that the samples with high preservation of active ingredients were products with production certificates based on laboratory analyzes. The samples were generally found to have inhibition activity against Gram (+) bacteria. Propolis samples P6 and P22 showed high activity against Gram (+) and Gram (-) bacteria and even fungi. When we evaluated some products that are insufficient in terms of content and antimicrobial activity, it was observed that antimicrobial activity increased depending on the other auxiliary chemicals used in the products. In this context, propolis products, which are very valuable in terms of health, may lose their real activity due to uncontrolled production and will gradually be devalued in the market. It is important that this valuable product should be produced and offered to the market with the necessary analysis methods without losing its effectiveness.en_US
dc.description.sponsorshipDuzce University Scientific Research Projects Support Program [BAP- 2021.05.03.1224]en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Project numbered BAP- 2021.05.03.1224 within the scope of Duzce University Scientific Research Projects Support Programen_US
dc.identifier.doi10.1016/j.microc.2024.111023
dc.identifier.issn0026-265X
dc.identifier.issn1095-9149
dc.identifier.scopus2-s2.0-85196420098en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.microc.2024.111023
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14297
dc.identifier.volume204en_US
dc.identifier.wosWOS:001259323400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMicrochemical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntimicrobial activityen_US
dc.subjectBioactive ingredienten_US
dc.subjectHPLCen_US
dc.subjectPropolisen_US
dc.subjectFlavonoiden_US
dc.subjectCommercial producten_US
dc.subjectBiological-Propertiesen_US
dc.subjectAlpha-Tocopherolen_US
dc.titleAnalysis and evaluation of quality parameters of commercial propolis products using a new high Performance Liquid Chromatography (HPLC) method and Comparison of antimicrobial propertiesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu