Synthesis of bromoaminoindane and bromoaminoindanone derivatives
Yükleniyor...
Dosyalar
Tarih
2013
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Science Reviews 2000 Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The bromination reactions of 5-aminoindane, 5-acetamidoindane, and 5-acetamidoindan-1-one were investigated using NBS, molecular bromine and photobromination, and the optimum reaction conditions were presented. The reaction of 5-aminoindane with glacial acetic acid at reflux temperature resulted in the formation of 5-acetamidoindane in high yield. 5-Acetamidoindan-1-one was generated by the reaction of 5-acetamidoindane with CrO3 in acetic acid. Selective bromination at C-6 position of 5-acetamidoindane was achieved by treatment of title compound with bromine in acetic acid and thus afforded 5-acetamido-6-bromoindane. Further bromination reactions of bromoindanones were achieved in various reaction conditions.
Açıklama
Erenler, Ramazan/0000-0002-0505-3190; Tutar, Ahmet/0000-0001-5524-8001
WOS: 000318899400013
WOS: 000318899400013
Anahtar Kelimeler
bromination reactions, bromoaminoindane, bromoaminoindanone
Kaynak
Journal Of Chemical Research
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
Sayı
4