Bioactive potential and topical formulation of black rice (Oryza sativa) extract compared with ferulic acid and arbutin
Küçük Resim Yok
Tarih
2026
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Black rice (Oryza sativa L.) is a rich source of phenolics and flavonoids, making it a candidate ingredient for dermocosmetic applications. This study aimed to evaluate the bioactive potential of an ethanolic black rice extract as a supportive ingredient by comparing its antioxidant capacity, tyrosinase inhibitory activity, and cytocompatibility with two established references, ferulic acid and arbutin, and by developing a stable topical formulation. The extract, containing 141.23 +/- 7.06 mg GAE/g phenolics and 96.75 +/- 4.84 mg QE/g flavonoids, exhibited a moderate total antioxidant capacity (46 mu mol TE mL-1). At a non-cytotoxic concentration (<= 0.1 % v/ v) that maintained over 90 % viability in HaCaT keratinocytes, its tyrosinase inhibition was limited compared to the reference compounds. A topical gel formulated with the extract exhibited acceptable physicochemical properties and remained stable in accelerated stability tests simulating a 2-year shelf life, showing no significant change in appearance, pH, viscosity, or microbiological quality. While the direct depigmenting effect was limited, black rice extract displays a positive biocompatibility and stability profile, supporting its potential role as a multifunctional, natural supporting ingredient in cosmetic formulations for oxidative balance and skincare. This provides a scientific basis for the future development of safe, naturally sourced skincare products containing black rice extract.
Açıklama
Anahtar Kelimeler
[Keyword Not Available]
Kaynak
South African Journal of Botany
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
190
