CUSHING DISEASE ASSOCIATED WITH RATHKE'S CLEFT CYST

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dc.contributor.authorBerker, Dilek
dc.contributor.authorAydın, Yusuf
dc.contributor.authorIşık, S.
dc.contributor.authorSöylemezoğlu, F.
dc.contributor.authorTütüncü, Y.
dc.contributor.authorBerker, Mustafa
dc.contributor.authorGüler, Serdar
dc.date.accessioned2020-05-01T09:11:16Z
dc.date.available2020-05-01T09:11:16Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000287017700009en_US
dc.description.abstractObjective. Co-existence of Cushing disease and Rathke's cleft cyst (RCC) has been reported in a few cases in the literature so far. We herein describe a rare condition of Cushing disease that might originate from epithelium of RCC. Case. A 48-year-old woman was admitted to the hospital with complaints of headache, weakness, and weight gain. The patient underwent endoscopic transsphenoidal surgery due to Cushing disease. Histopathological examination revealed cyst contents and walls compatible with RCC, and normal adenohypophysis and neurohypophysis tissues. Immunohistochemical stainings with ACTH, GH, and prolactin were positive on the epithelium of the cyst. Conclusion. In our case, Cushing disease might he associated with hormonal activity derived from cyst wall of RCC or disappearance of a small microadenoma during surgical or pathological processing. According to the recent data, origin of this lesion and histogenetic link between RCC with Cushing disease could not be explained.en_US
dc.identifier.doi10.4183/aeb.2010.371en_US
dc.identifier.endpage376en_US
dc.identifier.issn1841-0987
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage371en_US
dc.identifier.urihttps://doi.org/10.4183/aeb.2010.371
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5439
dc.identifier.volume6en_US
dc.identifier.wosWOS:000287017700009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofActa Endocrinologica-Bucharesten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRathke's cleft cysten_US
dc.subjectCushing diseaseen_US
dc.titleCUSHING DISEASE ASSOCIATED WITH RATHKE'S CLEFT CYSTen_US
dc.typeArticleen_US

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