An Updated Review on Ziziphora L.: A Valuable Source of Phytoconstituents for Potential Health Benefits

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dc.contributor.authorIlhan, Mert
dc.contributor.authorGurbuz, Perihan
dc.contributor.authorSuntar, Ipek
dc.date.accessioned2025-10-11T20:47:52Z
dc.date.available2025-10-11T20:47:52Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractZiziphora L. (Lamiaceae) is a genus of annual or perennial medicinal plants. These species are characterized by their aromatic features and are widely distributed across Southern and Eastern Europe, Asia, and North-West Africa. In T & uuml;rkiye, the genus comprises eleven taxa, namely Ziziphora clinopodioides Lam., Z. subsp. taurica, and Z. taurica Bieb. subsp. cleonioides (Boiss.) Davis. Ziziphora species have been used in Turkish, Kazakh, and Iranian folk medicine, especially in the form of infusion, decoction and maceration, owing to their antiseptic, expectorant, stomachic, carminative, and sedative effects. Ziziphora species have also been used against the common cold, coughing, migraine, fever, inflammation, diarrhea, and depression. There is a high number of studies documenting the phytochemical features and biological activities of Ziziphora species. Although the essential oil composition of the Ziziphora genus was the primary focus of earlier studies, these species also contain triterpenes, flavonoids, and phenolic acids. They were demonstrated to display antimicrobial, antioxidant, and immunomodulatory activities. Given their diverse biological activities and phytoconstituents, Ziziphora species represent a promising candidate for further pharmacological research. In the present review, ethnobotanical records, phytochemical profiles, and bioactivities of Ziziphora species will be extensively presented.en_US
dc.identifier.doi10.25135/rnp.523.2504.3496
dc.identifier.endpage399en_US
dc.identifier.issn1307-6167
dc.identifier.scopus2-s2.0-105010168778en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage375en_US
dc.identifier.urihttps://doi.org/10.25135/rnp.523.2504.3496
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21624
dc.identifier.volume19en_US
dc.identifier.wosWOS:001525214300004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAcg Publicationsen_US
dc.relation.ispartofRecords of Natural Productsen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectLamiaceaeen_US
dc.subjectZiziphoraen_US
dc.subjectethnobotanyen_US
dc.subjectbiological activityen_US
dc.subjectphytochemistryen_US
dc.titleAn Updated Review on Ziziphora L.: A Valuable Source of Phytoconstituents for Potential Health Benefitsen_US
dc.typeReviewen_US

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