Investigation of relationship of visceral body fat and inflammatory markers with metabolic syndrome and its components among apparently healthy individuals

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dc.contributor.authorTürker, Yasemin
dc.contributor.authorBaltacı, Davut
dc.contributor.authorTürker, Yasin
dc.contributor.authorÖztürk, Serkan
dc.contributor.authorSönmez, Cemil Işık
dc.contributor.authorDeler, Mehmet Harun
dc.contributor.authorAnkaralı, Handan
dc.date.accessioned2020-04-30T23:18:40Z
dc.date.available2020-04-30T23:18:40Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAnkarali, Handan Camdeviren/0000-0002-3613-0523en_US
dc.descriptionWOS: 000365271900131en_US
dc.descriptionPubMed: 26550229en_US
dc.description.abstractMetabolic syndrome is a cluster of disorders and great risk for cardiovascular diseases. We aimed to investigate association between severity of metabolic syndrome (MetS) and anthropometric measurements, and to evaluate correlation of MetS and its components with metabolic deterioration and inflammatory indexes. The cross-sectional study enrolled 1474 patients with obesity and overweight. The patients were grouped as MetS and Non-MetS, and were sub-grouped as group 1 (three criteria), 2 (four criteria) and 3 (>= five criteria) according to NCEP ATP III. Mean age was 38.7 +/- 11.9 years and BMI was 35.1 +/- 6.3 kg/m(2). Lipid profile, anthropometric and blood pressure measurements, liver function tests, bioelectric impedance body fat compositions, insulin resistance and HbA1c, and spot urinary albumin-creatinine ratio were significantly different between groups of MetS and Non-MetS. Age, lipid profile, bioelectric impedance fat analyses, BMI, blood pressure values, glucose, insulin resistance, uric acid and hs-CRP levels were significantly different between groups of MetS component groups. ROC analysis revealed that hs-CRP was found to be more predictive for severity of metabolic syndrome components 3 and 4 (P=0.030); uric acid and visceral fat were more actual to predict severity of metabolic syndrome between 3 and 5 MetS components, (P=0.006) and uric acid was detected as more actual to predict severity of MetS between 4 and 5 components (P=0.023). In conclusion, uric acid, hs-CRP and visceral body fat composition were useful to predict to severity of MetS in primary care.en_US
dc.identifier.endpage13077en_US
dc.identifier.issn1940-5901
dc.identifier.issue8en_US
dc.identifier.startpage13067en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3463
dc.identifier.volume8en_US
dc.identifier.wosWOS:000365271900131en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal Of Clinical And Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMetabolic syndromeen_US
dc.subjectprimary careen_US
dc.subjecturic aciden_US
dc.subjectHs-CRPen_US
dc.subjectbioelectric impedance fat analysisen_US
dc.titleInvestigation of relationship of visceral body fat and inflammatory markers with metabolic syndrome and its components among apparently healthy individualsen_US
dc.typeArticleen_US

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