Incidence, prevalence, and mortality estimates for chronic atrial fibrillation in Turkish adults

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dc.contributor.authorUyarel, Hüseyin
dc.contributor.authorOnat, Altan
dc.contributor.authorYüksel, Hüsniye
dc.contributor.authorCan, Günay
dc.contributor.authorOrdu, Serkan
dc.contributor.authorDursunoğlu, Dursun
dc.date.accessioned2020-04-30T13:32:35Z
dc.date.available2020-04-30T13:32:35Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionPubMed ID: 18765964en_US
dc.description.abstractObjectives: We investigated the incidence, prevalence, and mortality of chronic atrial fibrillation (AF) in Turkish adults. Study design: In a prospective and cross-sectional design, we analyzed 3,450 eligible participants (1707 men, 1743 women; mean age 52±13 years) of the Turkish Adult Risk Factor Study, who had been surveyed until 2006/07. Those who were dead and were found to have AF at base-line were excluded in the estimation of AF prevalence and incidence, respectively. Results: Atrial fibrillation was determined in 67 participants. The total follow-up was 34,100 person-years (mean 9.9 years). There were 43 prevalent and 46 incident cases, which corresponded to 1.25% and 1.35 per 1000 person-years, respectively. For age brackets of 32-59, 60-69, and ?70 years, the prevalence rates were 0.46%, 2.09%, and 2.49%, and the incidence rates were 0.31, 1.98, and 3.50 per 1000 person-years, respectively. Both were higher in women of all age groups, with female-to-male ratios for overall prevalence and incidence being 1.69 and 1.19, respectively. Survival after onset of AF was 5 to 9 years and overall mortality was 6.8 per 100 person-years. Hypertension was the most common cause of AF, followed by advanced age. Contrary to expectations, waist circumference of men with AF was smaller by 1.9 cm than that of women. Serum C-reactive protein levels in men with AF (mean 1.21 mg/I) were significantly lower than women with AF (mean 2.62 mg/l) and than males without AF (mean 1.78 mg/l). Conclusion: In Turkish adults, the current incidence and prevalence of chronic AF can be extrapolated to be 35,000 per year (22,000 in women) and 310,000 (200,000 in women), respectively. Considering the low incidence in males, it seems that inflammatory processes may play a minor role in the development of AF in Turkish men.en_US
dc.identifier.endpage222en_US
dc.identifier.issn1016-5169
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage214en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/362
dc.identifier.volume36en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtrial fibrillation/epidemiology; Cohort studies; Incidence; Prevalence; Sex distribution; Turkey/epidemiologyen_US
dc.titleIncidence, prevalence, and mortality estimates for chronic atrial fibrillation in Turkish adultsen_US
dc.title.alternativeTürk halkinda kronik atriyal fibrilasyon insidansi, prevalansi ve mortalitesine ilişkin tahminleren_US
dc.typeArticleen_US

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