Predictive Value of Volumetric Measurements of Fetal Adrenal Glands for Preterm Birth: A Case-Control Study

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dc.authoridGOYNUMER, FIKRET GOKHAN/0000-0002-3739-6008;
dc.contributor.authorBasbug, Alper
dc.contributor.authorYurtcu, Engin
dc.contributor.authorKeyif, Betul
dc.contributor.authorKaya, Aski Ellibes
dc.contributor.authorSungur, Mehmet Ali
dc.contributor.authorGoynumer, Fikret Gokhan
dc.contributor.authorHatirnaz, Safak
dc.date.accessioned2025-10-11T20:47:50Z
dc.date.available2025-10-11T20:47:50Z
dc.date.issued2024
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground: To investigate whether fetal adrenal gland volume (AGV) and fetal zone volume (FZV), important components of the fetal adrenal gland, differ between women who have term and preterm births, and to determine whether these two parameters can be used to predict premature birth. Methods: A total of 238 pregnant women at 24-28 weeks of gestation were included in this case-control study. The fetal AGV and FZV were ultrasonographically evaluated, and corrected AGV (cAGV) and corrected FZV (cFZV) were assessed with adjustments for estimated birth weight. Receiver operating characteristic (ROC) curves were used to assess the ability of AGV, FZV, cAGV, and cFZV to predict preterm birth. Results: Ultrasound exams on 220 term fetuses and 18 preterm fetuses showed that preterm fetuses exhibited higher AGV (p = 0.039), FZV (p = 0.001), cAGV (p = 0.001), and cFVZ (p = 0.001) compared to term fetuses. Conclusions: These results demonstrated that term and preterm fetuses differ in their AGV and FZV within this study population. The data generated by 3D sonography between 24 and 28 weeks of gestation may be beneficial for predicting premature birth. However, larger prospective studies with a larger sample size of preterm births are needed to validate these findings.en_US
dc.identifier.doi10.31083/j.ceog5108179
dc.identifier.issn0390-6663
dc.identifier.issn2709-0094
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-85203339135en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.urihttps://doi.org/10.31083/j.ceog5108179
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21606
dc.identifier.volume51en_US
dc.identifier.wosWOS:001312763100009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherImr Pressen_US
dc.relation.ispartofClinicaland Experimental Obstetrics & Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectfetal adrenal glanden_US
dc.subjectfetal zone volumeen_US
dc.subjectpreterm birthen_US
dc.subject3D ultrasounden_US
dc.titlePredictive Value of Volumetric Measurements of Fetal Adrenal Glands for Preterm Birth: A Case-Control Studyen_US
dc.typeArticleen_US

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