Clinicopathological Features of Extranodal Lymphomas: 15 Years' Experience of a Single Center

dc.contributor.authorCoskun, Sinem Kantarcioglu
dc.contributor.authorNazlioglu, Hulya Ozturk
dc.contributor.authorBuyukuysal, Cagatay
dc.date.accessioned2021-12-01T18:49:23Z
dc.date.available2021-12-01T18:49:23Z
dc.date.issued2021
dc.department[Belirlenecek]en_US
dc.description.abstractObjective: In this study, we aimed to evaluate the localization and histopathological diagnosis, and clinicopathologic characteristics of primary extranodal lymphomas. Methods: The pathology reports between 2001 and 2015 in the archives of Uludag University Faculty of Medicine Pathology Department were reviewed and all cases with an extranodal lymphoma diagnosis were analyzed. The information about the diagnosis, tumor localization, symptoms at presentation, presence of B symptoms, lymphocytosis and anemia, chronic infection and chronic disease and concomitant secondary malignancy, tumor diameter, the involvement of another extranodal organ, lymph node, bone marrow, spleen, liver, stage of the disease, serum B2 microglobulin, LDH, albumin levels, sedimentation rate were documented. The localization, histopathological types, age groups, male/female ratios in cases of primary extranodal lymphoma were evaluated. Results: Total sum of 1743 patients were diagnosed with lymphoma. 480 (%27,53) of these cases were extranodal lymphomas. The most commonly encountered locations of extranodal lymphomas were the skin and the gastrointestinal system. There were 226 primary extranodal skin, 90 gastrointestinal system, 44 central nervous system, 8 genitourinary system, 50 head and neck, 18 musculoskeletal system and soft tissue, 9 mediastinum, 3 bronchus, 10 orbital, 2 liver, 6 pancreas, 4 omentum, 8 endocrine system, and 2 breast located cases. 237 of the primary extranodal lymphomas from our work were mature T/NK celled neoplasias. There were 250 patients with mature B cell lymphoma, 5 cases of Hodgkin lymphoma, and 5 cases of precursor lymphoid neoplasia. Conclusions: The data from our series were coherent with the literature. Due to the small number of cases with some localization and some histopathological diagnosis, no significant results could be reached about these entities.en_US
dc.identifier.doi10.18521/ktd.789919
dc.identifier.endpage232en_US
dc.identifier.issn1309-3878
dc.identifier.issue2en_US
dc.identifier.startpage226en_US
dc.identifier.urihttps://doi.org/10.18521/ktd.789919
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10713
dc.identifier.volume13en_US
dc.identifier.wosWOS:000689729500010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherDuzce Univen_US
dc.relation.ispartofKonuralp Tıp Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectExtranodal Lymphomaen_US
dc.subjectSkinen_US
dc.subjectGastrointestinal Systemen_US
dc.subjectCentral Nervous Systemen_US
dc.subjectDiffuse Large B Cell Lymphomaen_US
dc.subjectCentral-Nervous-Systemen_US
dc.subjectNon-Hodgkins-Lymphomaen_US
dc.subjectCell Lymphomaen_US
dc.subjectEpidemiologyen_US
dc.subjectHeaden_US
dc.titleClinicopathological Features of Extranodal Lymphomas: 15 Years' Experience of a Single Centeren_US
dc.typeArticleen_US

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