Autistic feature and 2D:4D finger ratio relations children and adolescents with congenital adrenal hyperplasia

dc.contributor.authorKocaman, Gizem Melissa
dc.contributor.authorÖzmerdivenli, Recep
dc.contributor.authorYektaş, Çiğdem
dc.contributor.authorBolu, Semih
dc.contributor.authorHaskılıç, Yunus Emre
dc.contributor.authorErdoğan, Ayten
dc.date.accessioned2020-04-30T13:32:09Z
dc.date.available2020-04-30T13:32:09Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Because congenital adrenal hiperplazi (CAH) and autism spectrum sisorders (ASD) is rarely seen, it is difficult to assess whether the increased incidence of ASD in girls with CAH. ASD behaviors and 2D:4D finger ratio changes in patients with androgen overproduction have been reported. The aim of this study is determining the 2D:4D finger ratios and ASD features in girls with CAH and normal control group. Methods: The study group will consist of thirty female children and adolescents between the ages of 3 and 15 who are diagnosed with classic CAH who were followed at the Pediatric Endocrinology Department of Düzce University Medical Faculty Hospital. For the control group, 30 healthy children and adolescents equalized with CAH patients in terms of age and gender will be taken. Al patients and controls examined for psychiatric disorders. by clinicians Patients and control groups filled Autism Behavior Checlist and semistructured sociodemogrphic form that evaluated the gender, age, pregnancy and birth complications, history of mothers’ cigarette and alcohol use. 2D:4D ratios were measured in both of control and CAH groups. Results: KAH group right and left hand 2D:4D ratios were statistically lower compared to controls and also lower 2D:4D ratios had association with high ABC scores. When compared with control group, CAH group ABC scores were significantly higher. In KAH group there was a pozitive correlation between 2D:4D ratios and ABC scores. Conclusion: In light of present study findings, suggest that high androjen may have effect on low 2D:4D ratios and high ASD symptoms. Further researchs with a large sample are needed in this field. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.en_US
dc.identifier.doi10.5455/apd.239006en_US
dc.identifier.endpage403en_US
dc.identifier.issn1302-6631
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage395en_US
dc.identifier.urihttps://dx.doi.org/10.5455/apd.239006
dc.identifier.urihttps://hdl.handle.net/20.500.12684/118
dc.identifier.volume18en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherCukurova University, Faculty of Medicineen_US
dc.relation.ispartofAnadolu Psikiyatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject2D:4D rates; Androgen hormons; Autism; Behavior problems; Child; Congenital adrenal hyperplasia; Ergenen_US
dc.titleAutistic feature and 2D:4D finger ratio relations children and adolescents with congenital adrenal hyperplasiaen_US
dc.title.alternativeKonjenital adrenal hiperplazisi olan çocuk ve ergenlerde otistik özellikler ve 2D:4D parmak oranlarının ilişkisien_US
dc.typeArticleen_US

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