Hydrophilic deep eutectic solvent based microextraction procedure for the determination of four paraben preservatives in vitamin D for babies: A green approach

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dc.authorscopusid58482655900en_US
dc.authorscopusid57201291096en_US
dc.authorscopusid53867264800en_US
dc.contributor.authorAkmes, Ali
dc.contributor.authorDalmaz, Aslihan
dc.contributor.authorOzak, Sezen Sivrikaya
dc.date.accessioned2024-08-23T16:04:41Z
dc.date.available2024-08-23T16:04:41Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractIn this study, an easily available, sensitive, and fast hydrophilic deep eutectic solvent-liquid phase microextraction method developed using deep eutectic solvent (DES) as a green solvent for the determination and microextraction of paraben (methyl, ethyl, propyl, and butyl) preservatives in vitamin D for babies. The highest yield for extraction recovery was obtained using DES consisting of a 1:4 M ratio of choline chloride and acetic acid. Moreover, various optimization parameters such as DES volume, DES type, sample volume, and centrifugation time were investigated in order to develop a real sample specific microextraction method. Relative standard deviation values were 0.92%-2.87%, the detection limit was 0.194-0.254 & mu;g/mL, and extraction recovery values were between 87.40% and 102.98%. The method developed in this study was successfully applied to 5 different babies in vitamin D for babies obtained from pharmacies for the determination of methyl, ethyl, propyl, and butylparaben. As far as we know, it is the first study conducted both in terms of the determination of paraben preservatives in vitamin D for babies and in terms of the fact that DES used in this study is used for the first time in vitamin D for babies.en_US
dc.description.sponsorshipScientific and Technological Research Council of Tuuml;rkiye (TUBITAK) 2209-A-Research Project Sup-port Programme for Undergraduate Students Project Fund [1919B012108426]; Duzce University Scientific Research Projects Fund [2022-05-03-1327]en_US
dc.description.sponsorshipThis research was supported by the Scientific and Technological Research Council of Turkiye (TUBITAK) 2209-A-Research Project Sup-port Programme for Undergraduate Students Project Fund (Project No: 1919B012108426) and Duzce University Scientific Research Projects Fund (Project No: 2022-05-03-1327) for contributing to the financial portion of the project. This manuscript is a 3rd birthday present for our Lab friend dear Kaan Ozak.en_US
dc.identifier.doi10.1016/j.microc.2023.109013
dc.identifier.issn0026-265X
dc.identifier.issn1095-9149
dc.identifier.scopus2-s2.0-85164452613en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.microc.2023.109013
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14299
dc.identifier.volume193en_US
dc.identifier.wosWOS:001029738900001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMicrochemical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectParabenen_US
dc.subjectMicroextractionen_US
dc.subjectGreen chemistryen_US
dc.subjectDeep eutectic solventen_US
dc.subjectVitamin Den_US
dc.subjectLiquid-Liquid Microextractionen_US
dc.subjectGas-Chromatographyen_US
dc.subjectCosmetic Productsen_US
dc.subjectExtractionen_US
dc.subjectSamplesen_US
dc.subjectPreconcentrationen_US
dc.subjectAssayen_US
dc.subjectAciden_US
dc.titleHydrophilic deep eutectic solvent based microextraction procedure for the determination of four paraben preservatives in vitamin D for babies: A green approachen_US
dc.typeArticleen_US

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