Anemia and Red Blood Cell Transfusion Practices in a Medical Intensive Care Unit

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dc.contributor.authorAkbaş, Türkay
dc.contributor.authorBalbay, Öner Abidin
dc.date.accessioned2023-07-26T11:57:49Z
dc.date.available2023-07-26T11:57:49Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: The study was aimed to describe red blood cell (RBC) transfusion practices in a medical intensive care unit (ICU). Material and Method: This retrospective study involved patients admitted to the ICU between September 2015 and February 2020. A restrictive transfusion strategy was applied during the study period, in which hemoglobin levels were kept between 7.0 and 9.0 g/dL, and the recommended threshold for RBC transfusion was <7 g/dL, except for patients with acute coronary disease, acute cerebrovascular event, heart failure, severe hypoxemia, or undergoing hip fracture surgery, for whom hemoglobin levels were kept at >= 8 g/dL. Results: Six hundred seventeen patients were included in the study (age 70 +/- 16 years, 51.7% male), with a mean hemoglobin level of 11.1 +/- 2.3 g/dL on admission. RBC transfusion was performed on 204 (33.1%) patients, and admission hemoglobin levels were significantly lower in the transfused than the non-transfused patients (9.4 +/- 1.9 vs. 11.9 +/- 2.1 g/dL; p<0.001). An average of 3.5 units per patient was transfused. Transfused patients had high disease severity scores, required high rates of invasive mechanical ventilation, renal replacement therapy and vasopressor use, and had longer ICU and hospital stays. ICU, in-hospital, 28-day, and 90-day mortality rates were significantly high among transfused patients. Logistic regression analysis identified RBC transfusion as an important predictor of 28-day (OR, 2.51; 95% CI, 1.49-4.23, p=0.001) and 90-day (OR, 1.69; 95% CI, 1.25-2.28; p=0.001) mortality. Conclusion: Patients receiving RBC transfusion have high disease severity scores, exhibit low admission hemoglobin levels, require more organ support therapies, and have high mortality rates. The presence of RBC transfusion is a significant predictor of mortality.en_US
dc.identifier.doi10.37678/dcybd.2022.3111
dc.identifier.endpage47en_US
dc.identifier.issn2717-6428
dc.identifier.issue2en_US
dc.identifier.startpage43en_US
dc.identifier.trdizinid1128418en_US
dc.identifier.urihttps://doi.org/10.37678/dcybd.2022.3111
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1128418
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13316
dc.identifier.volume13en_US
dc.identifier.wosWOS:000815129200001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorAkbas, Turkay
dc.institutionauthorBalbay, Öner Abidin
dc.language.isoenen_US
dc.publisherSoc Turkish Intensivists - Stien_US
dc.relation.ispartofJournal of Critical & Intensive Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectCritical Illness; Anemia; Blood Transfusion; Mortalityen_US
dc.subjectLength-Of-Stay; Critically-Ill; Icuen_US
dc.titleAnemia and Red Blood Cell Transfusion Practices in a Medical Intensive Care Uniten_US
dc.typeArticleen_US

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