The Effectiveness of New Oral Anticoagulants in theTreatment of Lower Extremity Venous Thrombosis: ARetrospective Clinical Study

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dc.contributor.authorDüzgün, Ali Cemal
dc.contributor.authorİlkeli, Ekin
dc.date.accessioned2023-07-26T11:58:19Z
dc.date.available2023-07-26T11:58:19Z
dc.date.issued2021
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractObjective: This clinical study included a retrospective evaluation of 138 patients using new oralanticoagulants (rivaroxaban, dabigatran, apixaban, edoxaban) for lower extremity deep veinthrombosis.Methods: 138 patients using new oral anticoagulant drugs were included in the retrospective study.Demographic characteristics, diagnosis and treatment charts, radiological images, epicrisis notes ofthe patients were recorded. Records of each patient were reviewed during their 12 months of follow- up. New oral anticoagulant efficacy; It was evaluated by measuring thigh and calf diameters beforeand after treatment, whether there was recanalization in Doppler USG (recanalization> 75%),recanalization time, bleeding side effects and recovery times with treatment, and recurrence rates.The data were analyzed statistically using a statistics program.Results: A significant difference was found when the mean thigh diameter measurements measuredat the beginning of the treatment (Mean ± SD: 75,41) and the mean thigh diameter measured afterthe treatment (Mean ± SD: 54,63) were compared (p<0.05). A significant difference was foundwhen the mean calf diameter measurements (Mean ± SD: 43.99) measured at the beginning of thetreatment and the mean calf diameter measured after the treatment were compared (p<0.05). Post- treatment Doppler USG showed complete recanalization rate in 54% (75 patients) at 3 months and25% (35 patients) at 6 months. At the end of the 6th month, the total recanalization rate occurred in80% (110) patients.Conclusions: New oral anticoagulants (rivaroxaban, dabigatran, apixaban, edoxaban) are veryeffective in the treatment of lower extremity deep venous thrombosis, both in providingrecanalization and in terms of clinical improvement in early and midterm.en_US
dc.identifier.doi10.18521/ktd.807493
dc.identifier.endpage318en_US
dc.identifier.issn1309-3878
dc.identifier.issue2en_US
dc.identifier.startpage312en_US
dc.identifier.trdizinid467294en_US
dc.identifier.urihttp://doi.org/10.18521/ktd.807493
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/467294
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13460
dc.identifier.volume13en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorİlkeli, Ekin
dc.language.isoenen_US
dc.relation.ispartofKONURALP TIP DERGİSİen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.titleThe Effectiveness of New Oral Anticoagulants in theTreatment of Lower Extremity Venous Thrombosis: ARetrospective Clinical Studyen_US
dc.typeArticleen_US

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