ASSOCIATION BETWEEN BLOOD UREA NITROGEN/ALBUMIN RATIO AND PROGNOSIS IN NON-SMALL CELL LUNG CANCER

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dc.contributor.authorKöş, Mehmet
dc.contributor.authorHocazade, Cemil
dc.contributor.authorKöş, Fahriye Tuğba
dc.contributor.authorUncu, Doğan
dc.contributor.authorKarakaş, Esra
dc.contributor.authorDoğan, Mutlu
dc.contributor.authorZengin, Nurullah
dc.date.accessioned2020-04-30T22:39:50Z
dc.date.available2020-04-30T22:39:50Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000363826100001en_US
dc.description.abstractIntroduction: Prognostic value of easily available and reproducible laboratory parameters is investigated for non-small cell lung cancer (NSCLC) of which mortality is still high. We aimed to determine the prognostic value of blood urea nitrogen/albumin (BUN/albumin) ratio. Methods: ClinicoPathological characteristics with treatment modalities and laboratory values of NSCLC patients at our center evaluated retrospectively. A total of 142 patients were included to the study. Results: Median age was 57 (range 26-83). Receiver operating characteristic (ROC) curves for overall survival prediction were plotted to verify, the optimum cut-off point for BUN/albumin ratio. The recommended cut-off values for BUN/albumin ratio was 0.80 with a sensitivity of 60.0% and a specificity of 60.0%. While median overall survival was 26.0 (95% CI: 14.2-37.7) months in the group with low BUN/albumin ratio (<0.80), it was Calculated as 10.0 (95% CI: 5.2-14.8) months in the group with high BUN/albumin ratio (>= 0.80). The difference between groups was statistically significant (p=0.005). Conclusion: BUN/albumin ratio seems to be a significant prognostic index in NSCLC. It is not only simple but also inexpensive and reproducible. However, it needs further prospective trials with large number of patients.en_US
dc.identifier.endpage223en_US
dc.identifier.issn0393-6384
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage219en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2839
dc.identifier.volume31en_US
dc.identifier.wosWOS:000363826100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBlood Urea Nitrogenen_US
dc.subjectAlbuminen_US
dc.subjectRatioen_US
dc.subjectPrognosisen_US
dc.subjectNon-small Cell Lung Canceren_US
dc.titleASSOCIATION BETWEEN BLOOD UREA NITROGEN/ALBUMIN RATIO AND PROGNOSIS IN NON-SMALL CELL LUNG CANCERen_US
dc.typeArticleen_US

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