EVALUATION OF THE RELATION BETWEEN PRIMARY HYPERPARATHYROIDISM AND CONCOMITANT THYROID DISEASE

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dc.contributor.authorÖzuğuz, Ufuk
dc.contributor.authorIşık, Serhat
dc.contributor.authorAkbaba, Gülhan
dc.contributor.authorBerker, Dilek
dc.contributor.authorTütüncü, Yasemin
dc.contributor.authorAydın, Yusuf
dc.contributor.authorGüler, Serdar
dc.date.accessioned2020-05-01T12:14:12Z
dc.date.available2020-05-01T12:14:12Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000287017600006en_US
dc.description.abstractObjective. Thyroid diseases coexisting with primary hyperparathyroidism (PHPT) may individually change the diagnosis, treatment and follow-up of the patients. In our study, we aimed to investigate the thyroid diseases coexisting with PHPT and the relation between these two clinical situations. Methods. We retrospectively investigated 255 patients who were diagnosed as PHPT between 2004-2009 in our clinic. The general characteristics of the patients, laboratory tests, which were performed preoperatively, neck ultrasonography, thyroid and parathyroid scintigraphy and fine needle aspiration biopsy (FNAB) results were assessed. Cytological results of the nodules with preoperative FNAB were compared with the postoperative histological results. Results. Of the patients, 49 were male (19.2%) and 206 were female (80.8%). Mean age was 54.5+/-12.8. Bilateral neck exploration (BNE) was performed on 69 cases (27%), minimal invasive parathyroidectomy (MIP) on 78 cases (30.5%) and BNE plus thyroidectomy on 108 cases (42.5%). When all thyroid diseases were taken into account, prevalence of the coexisting thyroid disease was 65%, prevalence of nodular thyroid disease 52.1%, thyroid cancer 16.7% and thyroid dysfunction 11.8%. The mean age of the patients with a nodular goitre was significantly higher than of the patients who did not have nodules (p<0.001). General demographic data, calcium and PTH levels did not show any difference. Number of nodules was correlated with age (p<0.001, r=0.227). Conclusion. The relation between PHPT and nodular thyroid diseases is coincidental and this can be explained by the fact that both diseases occur in advanced age.en_US
dc.identifier.doi10.4183/aeb.2010.191en_US
dc.identifier.endpage202en_US
dc.identifier.issn1841-0987
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage191en_US
dc.identifier.urihttps://doi.org/10.4183/aeb.2010.191
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6328
dc.identifier.volume6en_US
dc.identifier.wosWOS:000287017600006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofActa Endocrinologica-Bucharesten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPrimary hyperparathyroidismen_US
dc.subjectnodular goitreen_US
dc.subjectthyroid carcinomaen_US
dc.titleEVALUATION OF THE RELATION BETWEEN PRIMARY HYPERPARATHYROIDISM AND CONCOMITANT THYROID DISEASEen_US
dc.typeArticleen_US

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