Postmenopozal Kadınlarda Lipid Düzeyleri Ve Kemik Mineral Yoğunluğu Arasındaki İlişki
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Dosyalar
Tarih
2010
Dergi Başlığı
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Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmanın amacı postmenapozal kadınlarda lipid düzeyleri ile kemik mineral yoğunluğu arasındaki ilişkiyi araştırmaktır. Yöntem: Çalışmaya Düzce Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon AD. polikliniğine başvuran 45-65 yaşları arası (ortalama yaş 54) 276 postmenopozal kadın alındı. Lomber vertebra ve femur boynu kemik mineral yoğunlukları dual enerji X ray absorbsiyometre ile, 12 saat süren açlık sonrası alınan kan örneklerinden serum total kolesterol, lipoproteinler ve trigliserid ölçüldü Çalışmaya hormon replasman ve lipid düzeyi düşürücü tedavi alanlar dahil edilmedi. Çalışmaya alınan tüm kadınlara osteoporoz sorgulama formu dolduruldu. Bulgular: Serum lipoproteinleri, total kolesterol ve trigliserid ile femur boynu ve lomber vertebra kemik mineral yoğunlukları arasında anlamlılık bulunamadı (p0,05). Yüksek vücut kitle indeksi ile femur boynu ve lomber vertebrada yüksek kemik mineral yoğunluğu istatistiksel olarak anlamlı bulundu (p0,001). Sonuç: Postmenopozal kadınlarda kemik mineral yoğunluğu ile lipid düzeyleri arasında istatistiksel olarak anlamlı bir ilişki bulunamadı.
Objective: The aim of this study is to investigate the relationship between lipid levels and bone mineral density in postmenopausal women Methods: We studied 276 postmenopausal women aged 45- 65 years (mean 54 years) who attended Duzce University faculty of medicine physical medicine and rehabilitation polyclinic. Bone mineral density in the lumbar spine and femur neck were measured by dual energy X-ray absorptiometry. Serum cholesterol, lipoproteins and triglyceride were assessed on a blood sample obtained after a 12-hour fast. All participants were given a questionnaire to answer on various risk factors for osteoporosis. Participants who reported the use of hormone replacement therapy and lipid lowering therapy were excluded. Statistically significant associations were found by SPSS 11.0 and p<0.05 was significant. Results: At baseline serum lipoproteins, total cholesterol and triglycerides didnt show significant correlation with bone mineral density at femur neck and lumbar spine. (Both p>0,05) higher body mass index is associated with higher bone mineral density at femur neck and lumbar spine (both p values <0,001). Conclusion: There is no significant relation between bone mineral density and lipid levels in postmenopausal women.
Objective: The aim of this study is to investigate the relationship between lipid levels and bone mineral density in postmenopausal women Methods: We studied 276 postmenopausal women aged 45- 65 years (mean 54 years) who attended Duzce University faculty of medicine physical medicine and rehabilitation polyclinic. Bone mineral density in the lumbar spine and femur neck were measured by dual energy X-ray absorptiometry. Serum cholesterol, lipoproteins and triglyceride were assessed on a blood sample obtained after a 12-hour fast. All participants were given a questionnaire to answer on various risk factors for osteoporosis. Participants who reported the use of hormone replacement therapy and lipid lowering therapy were excluded. Statistically significant associations were found by SPSS 11.0 and p<0.05 was significant. Results: At baseline serum lipoproteins, total cholesterol and triglycerides didnt show significant correlation with bone mineral density at femur neck and lumbar spine. (Both p>0,05) higher body mass index is associated with higher bone mineral density at femur neck and lumbar spine (both p values <0,001). Conclusion: There is no significant relation between bone mineral density and lipid levels in postmenopausal women.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp
Kaynak
Düzce Tıp Fakültesi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
12
Sayı
2