COVID-19 and Rheumatic Diseases

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dc.contributor.authorKimyon, Gezmiş
dc.contributor.authorDuman, Taşkın
dc.date.accessioned2023-04-10T20:19:32Z
dc.date.available2023-04-10T20:19:32Z
dc.date.issued2020
dc.departmentRektörlük, Rektörlüğe Bağlı Birimler, Düzce Üniversitesi Dergilerien_US
dc.description.abstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an infectious agentaffecting respiratory system the most and spreads rapidly due to large number of ACE2receptors in the lung. Arthralgia and myalgia are the most common rheumatologic findings,but arthritis is rare. Hyperinflammatory condition called cytokine storm causes acuterespiratory distress syndrome (ARDS) leading to death. Although coronavirus disease 2019(COVID-19) is mild or asymptomatic in most cases, it may progress to pneumonia and ARDS,especially in elderly patients who have comorbidities. Drugs such as tocilizumab whichsuppress inflammatory response and reduce cytokine storm may be effective on treatingCOVID-19 pneumonia. Cytokine storm, the cause of which is not fully understood and inwhich many structures of immune system interact with each other, is quite complex and hasdifferent mechanisms contributing to it. Although antimalarial drugs such ashydroxychloroquine are used in the treatment, there is no definite evidence that they areeffective. It has been shown that the prevalence and course of COVID-19 in rheumatic diseasesis similar to the general population, and that increasing age and additional comorbid conditionsincrease the risk of mortality. It is recommended that anti-rheumatic drugs used in the treatmentof rheumatic diseases should not be stopped unless the patient is infected with COVID-19.en_US
dc.identifier.doi10.18678/dtfd.788147
dc.identifier.endpage18en_US
dc.identifier.issn1307-671X
dc.identifier.issueS1en_US
dc.identifier.startpage14en_US
dc.identifier.trdizinid386441en_US
dc.identifier.urihttp://doi.org/10.18678/dtfd.788147
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/386441
dc.identifier.urihttps://hdl.handle.net/20.500.12684/11403
dc.identifier.volume22en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleCOVID-19 and Rheumatic Diseasesen_US
dc.typeArticleen_US

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