Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications

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2020

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info:eu-repo/semantics/openAccess

Özet

Common variable immune deficiency (CVID) is a rare primary immunodeficiency disorderthat is characterized by defective antibody production and inadequate B cell differentiation.While frequently recurrent respiratory tract infections are the most prominent clinical featurein CVID patients, CVID is a heterogeneous immune deficiency disorder that involves manysystems and organs such as lymphoid hyperplasia, autoimmune cytopenia, chronic lungdiseases, granulomatous diseases and susceptibility to malignancy. This may lead to delay indiagnosis and immunoglobulin replacement therapy, not being able to receive antibiotics at theappropriate dose and time, chronic inflammation, and therefore secondary amyloidosis. In thiscase report it is aimed to present a CVID patient with autoimmune complications anddeveloping renal amyloidosis during follow-up.

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22

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1

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