Heart rate turbulence and heart rate variability in patients with mitral valve prolapse

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dc.contributor.authorGündüz , Hüseyin
dc.contributor.authorArınç, Hüseyin
dc.contributor.authorKayardı, Mahmut
dc.contributor.authorAkdemir, Ramazan
dc.contributor.authorÖzyıldırım, Serhan
dc.contributor.authorUyan, Cihangir
dc.date.accessioned2020-05-01T12:10:18Z
dc.date.available2020-05-01T12:10:18Z
dc.date.issued2006
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000239365100012en_US
dc.descriptionPubMed: 16798765en_US
dc.description.abstractAims Heart rate turbulence (HRT) and heart rate variability (HRV) have been shown to be independent and powerful predictors of mortality in a specific group of cardiac patients. However, the predictive valsue of HRV alone is modest and information on HRV in patients with mitral valve protapse (MVP) has so far been conflicting. In addition, no studies have previously evaluated HRT in patients with MVP. To define better the effects of MVP on cardiac autonomic function, we assessed HRT and time-domain parameters of HRV in patients with MVP. Methods and results Fifty patients with MVP and 70 controls without MVP were investigated. The diagnosis of MVP was confirmed by cross-sectional echocardiography in the parasternal long-axis view and apicat 4-chamber view. The HRV and turbulence analysis were assessed from a 24-hour Hotter recording. When HRT parameters were compared, the values of the HRT onset and slope were significantly lower in MVP patients than in the controls group (-0.109 +/- 0.207 vs. -0.289 +/- 0.170%, P = 0.001 and 8.6 +/- 7.2 vs. 11.5 +/- 7.4 ms/RRI, P = 0.043, respectively) and the number of patients who had abnormal HRT onset was significantly higher in the MVP group than in controls (15 vs. 8, P = 0.011). In addition, HRV parameters were not statistically different between the two groups. Conclusion Although we found that the decrease in HRV parameters was not significantly different between MVP patients and controls, HRT variables (especially HRT onset) were significantly lower in MVP patients. Therefore, in our opinion, HRT is an attractive, easily applicable, and better way of non-invasive risk prediction compared with another non-invasive risk predictor, HRV.en_US
dc.identifier.doi10.1093/europace/eul059en_US
dc.identifier.endpage520en_US
dc.identifier.issn1099-5129
dc.identifier.issn1532-2092
dc.identifier.issue7en_US
dc.identifier.startpage515en_US
dc.identifier.urihttps://doi.org/10.1093/europace/eul059
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6130
dc.identifier.volume8en_US
dc.identifier.wosWOS:000239365100012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofEuropaceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmitral valve prolapseen_US
dc.subjectheart rate turbulenceen_US
dc.titleHeart rate turbulence and heart rate variability in patients with mitral valve prolapseen_US
dc.typeArticleen_US

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