Relationship between arterial blood gas values, pulmonary function tests and treadmill exercise testing parameters in patients with COPD

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dc.contributor.authorYazıcı, Mehmet
dc.contributor.authorArbak, Peri Meram
dc.contributor.authorBalbay, Öner Abidin
dc.contributor.authorMaden, Emin
dc.contributor.authorErbaş, Mete
dc.contributor.authorErbilen, Enver
dc.contributor.authorUyan, Cihangir
dc.date.accessioned2020-04-30T23:31:36Z
dc.date.available2020-04-30T23:31:36Z
dc.date.issued2004
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000224419300005en_US
dc.descriptionPubMed: 15363002en_US
dc.description.abstractObjective: There have been controversial reports regarding the relationship between exercise tolerance and resting pulmonary function in patients with COPD. The aim of this study was to examine the relationship between resting pulmonary function tests (rPFT) and cardiopulmonary exercise testing parameters (CETP) and their value in estimating exercise tolerance of patients. Methodology: In total, 45 patients with COPD (nine females, 36 males; mean age 61.2 +/- 11.2) and 21 healthy subjects (four females, 17 males; mean age 60.3 +/- 9.7) as a control group were studied. COPD patients (group I) were divided into three subgroups according to their FEV1 (mild/group II: FEV1 60-79% of predicted; moderate/group III: FEV1 40-59%; severe/group IV. FEV1 < 40%). In controls FEV1 was greater than or equal to 80%. Results: There were significant correlations between FEV1 and CETP in group III (maximal O-2 consumption (mVO(2)), r = 0.35, P < 0.005; total treadmill time (TTT), r = 0.31, P < 0.01; total metabolic equivalent values (TMET), r = 0.29, P < 0. 01)) and in group IV (mVO(2), r = 0.49, P < 0.001; TTT, r = 0.45, P < 0.005; TMET, r = 0.31, P < 0.01; peak heart rate (pHR), r = 0.29, P < 0.02; frequency of ventricular extrasystole (fVES), r = -0.27, P < 0.05). Additionally, in group IV there were significant correlations between PaO2 and CETP (mVO(2), r = 0.41, P < 0.02; TTT, r = 0.38, P < 0.03; TMET, r = 0.31, P < 0.05; pHR, r = 0.29, P < 0.05; fVES, r = -0.28, P < 0.05). Conclusion: There are significant correlations of resting FEV1% predicted and PaO2 Values with CETP in patients with moderate and severe COPD and these parameters may also have a role as indicators of exercise tolerance in these COPD patients.en_US
dc.identifier.doi10.1111/j.1440-1843.2004.00619.xen_US
dc.identifier.endpage325en_US
dc.identifier.issn1323-7799
dc.identifier.issn1440-1843
dc.identifier.issue3en_US
dc.identifier.startpage320en_US
dc.identifier.urihttps://doi.org/10.1111/j.1440-1843.2004.00619.x
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4348
dc.identifier.volume9en_US
dc.identifier.wosWOS:000224419300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofRespirologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCOPDen_US
dc.subjecttreadmill exercise testingen_US
dc.titleRelationship between arterial blood gas values, pulmonary function tests and treadmill exercise testing parameters in patients with COPDen_US
dc.typeArticleen_US

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