Psoas muscle mass, nutritional status, inflammation, and their relationship with prognosis in patients with pancreatic adenocarcinoma

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dc.authorscopusid57221085032
dc.authorscopusid55804436600
dc.authorscopusid57207826720
dc.authorscopusid57220604054
dc.authorscopusid23976227300
dc.authorscopusid57191259441
dc.contributor.authorYıldırım, İ.
dc.contributor.authorKaya, T.
dc.contributor.authorİşsever, K.
dc.contributor.authorGenç, A. C.
dc.contributor.authorKaracan, A.
dc.contributor.authorÖnmez, A.
dc.contributor.authorHacıbekiroğlu, İ.
dc.date.accessioned2021-12-01T18:38:48Z
dc.date.available2021-12-01T18:38:48Z
dc.date.issued2021
dc.department[Belirlenecek]en_US
dc.description.abstractIntroduction: some factors have been shown to be associated with survival in patients with pancreatic adenocarcinoma. Recently, some studies suggested that malnutrition, muscle mass, and inflammation might have an effect on survival in patients with pancreatic malignancy. Objectives: to investigate the association between psoas muscle mass, inflammation, nutritional status at the time of diagnosis, and survival in patients with pancreatic adenocarcinoma. Methods: this retrospective study included 219 patients diagnosed with pancreatic carcinoma. The nutritional status, inflammation, and psoas muscle mass of the patients at the time of diagnosis were evaluated. Nutritional status was assessed using the Prognostic Nutritional Index (PNI). Leucocyte count and neutrophil/lymphocyte ratio (NLR) were used for inflammation assessment. Psoas muscle mass was calculated by using abdominal computed tomography images of the patients. Results: the mean age of patients (80 female and 139 male) was 66.6 ± 11.7 years. According to the PNI results, 155 patients had a normal nutritional status (70 %), whereas 64 patients were malnourished (30 %). The survival of the patients with normal nutritional status was significantly longer than that of those who were malnourished (p < 0.001). There was no significant relationship between psoas muscle area, leucocyte count, NLR, and survival time. Conclusion: the survival of pancreatic adenocarcinoma patients with malnutrition at the time of diagnosis was significantly shorter than for patients without malnutrition. © 2021 SENPE y©Arán Ediciones S.L.en_US
dc.identifier.doi10.20960/nh.03573
dc.identifier.endpage1015en_US
dc.identifier.issn02121611
dc.identifier.issue5en_US
dc.identifier.pmid34223769en_US
dc.identifier.scopus2-s2.0-85118131525en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1009en_US
dc.identifier.urihttps://doi.org/10.20960/nh.03573
dc.identifier.urihttps://hdl.handle.net/20.500.12684/9845
dc.identifier.volume38en_US
dc.identifier.wosWOS:000754885100016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherARAN Ediciones S.A.en_US
dc.relation.ispartofNutricion Hospitalariaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMalnutritionen_US
dc.subjectPancreatic adenocarcinomaen_US
dc.subjectPsoas muscle areaen_US
dc.subjectSarcopeniaen_US
dc.subjectSurvivalen_US
dc.titlePsoas muscle mass, nutritional status, inflammation, and their relationship with prognosis in patients with pancreatic adenocarcinomaen_US
dc.typeArticleen_US

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