Bioactive contents, In vitro antiradical, antimicrobial and cytotoxic properties of rhubarb (Rheum ribes L.) extracts

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dc.contributor.authorKeser, Serhat
dc.contributor.authorKeser, Fatma
dc.contributor.authorKaratepe, Mustafa
dc.contributor.authorKaygılı, Ömer
dc.contributor.authorTekin, Suat
dc.contributor.authorTürkoğlu, İsmail
dc.contributor.authorSandal, Süleyman
dc.date.accessioned2020-04-30T13:32:10Z
dc.date.available2020-04-30T13:32:10Z
dc.date.issued2019
dc.departmentDÜ, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümüen_US
dc.description.abstractRheum ribes L. (rhubarb) is belonging to Polygonaceae, and its roots and fresh shoots are consumed as vegetable in Turkey. This plant is considered to be one of the most important pharmaceutical raw materials in Middle East. In this study, the antiradical, antimicrobial, cytotoxic and bioactive properties of water, ethanol, and methanol extracts of R. ribes stems were determined. R. ribes stems water, ethanol and methanol extracts are better scavenged ABTS•+ (99.27, 99.91, and 99.88%), DPPH• (83.11, 81.42, and 83.26%), and OH• radicals (93.49, 94.21, 95.86%) than standard antioxidant BHA (95.32, 80.49, and 93.78%). Stems of R. ribes abundantly include bioactive compounds, dominated by rutin, catechin, caffeic acid, ferulic acid, ?-tocopherol and vitamin D. These extracts show effective cytotoxic properties against PC-3, A2780, HCT-116 and MCF-7 cancer cell lines at 24h. It is found that R. ribes contain high amount important bioactive contents, and has effective antiradical and cytotoxic properties. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.en_US
dc.identifier.doi10.1080/14786419.2018.1560294en_US
dc.identifier.issn1478-6419
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.1080/14786419.2018.1560294
dc.identifier.urihttps://hdl.handle.net/20.500.12684/126
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofNatural Product Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantimicrobial; antiradical; cytotoxicity; phytosterol; Rhubarben_US
dc.titleBioactive contents, In vitro antiradical, antimicrobial and cytotoxic properties of rhubarb (Rheum ribes L.) extractsen_US
dc.typeArticleen_US

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