Evaluation of the Antimicrobial Activity of Glass Ionomer Luting Cement with Chlorhexidine Diacetate

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dc.contributor.authorAta, Seçil Özkan
dc.contributor.authorAkay, Canan
dc.contributor.authorMumcu, Emre
dc.contributor.authorErdönmez Bariş, Demet
dc.date.accessioned2026-07-01T11:36:29Z
dc.date.available2026-07-01T11:36:29Z
dc.date.issued2025
dc.departmentDüzce Üniversitesi
dc.description.abstractObjective: This study aimed to evaluate the antimicrobial activities of glass ionomer luting cements modified with chlorhexidine diacetate. Methods: Chlorhexidine diacetate (CXD) was incorporated into glass ionomer luting powder at 0 %, 1 %, 2%, 3% concentration and 120 round-shaped samples were prepared. Antimicrobial properties against Streptococcus mutans (S. mutans), Enterococcus faecalis (E. faecalis), and Candida albicans (C. albicans) were assessed with MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] and Cristal Violet Assay. Biofilms on samples were also observed by Scanning Electron Microscopy. One-way ANOVA and Tukey Tests were used for statistical analysis. Results: The highest amount of antimicrobial activity was found in samples with 3% added CXD. The proportion of viable pathogens were reduced significantly with the addition of 2% and 3 % CXD (P <.05). A noticeable reduction of S. mutans amount was seen with incorporation of 3% CXD (P <.05). S. mutans and C. albicans were inhibited significantly by all the samples when compared to control groups. Conclusions: Addition of 2%-3% CXD to glass ionomer luting cements increased the antimicrobial properties. As, microorganisms’ growth rate was inhibited in 3% CXD group, CXD added glass ionomer luting cement can be suggested in endodontically treated teeth, in high caries-risk patients, also in immunocompromised patients. © 2025, Ataturk Universitesi. All rights reserved.
dc.identifier.doi10.17567/currresdentsci.1433375
dc.identifier.endpage330
dc.identifier.issn2822-2555
dc.identifier.issue4
dc.identifier.scopus2-s2.0-105022844121
dc.identifier.scopusqualityQ4
dc.identifier.startpage326
dc.identifier.urihttps://doi.org/10.17567/currresdentsci.1433375
dc.identifier.urihttps://hdl.handle.net/20.500.12684/23067
dc.identifier.volume35
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAtaturk Universitesi
dc.relation.ispartofCurrent Research in Dental Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20260623
dc.subjectantibacterial
dc.subjectAntifungal
dc.subjectchlorhexidine diacetate
dc.subjectglass ionomer
dc.subjectluting cements
dc.titleEvaluation of the Antimicrobial Activity of Glass Ionomer Luting Cement with Chlorhexidine Diacetate
dc.title.alternativeKlorheksidin Diasetatlı Cam İyonomer Yapıştırma Çimentosunun Antimikrobiyal Aktivitesinin Değerlendirilmesi]
dc.typeArticle

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