Evaluation of the Antimicrobial Activity of Glass Ionomer Luting Cement with Chlorhexidine Diacetate
Küçük Resim Yok
Tarih
2025
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Ataturk Universitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: This study aimed to evaluate the antimicrobial activities of glass ionomer luting cements modified with chlorhexidine diacetate. Methods: Chlorhexidine diacetate (CXD) was incorporated into glass ionomer luting powder at 0 %, 1 %, 2%, 3% concentration and 120 round-shaped samples were prepared. Antimicrobial properties against Streptococcus mutans (S. mutans), Enterococcus faecalis (E. faecalis), and Candida albicans (C. albicans) were assessed with MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] and Cristal Violet Assay. Biofilms on samples were also observed by Scanning Electron Microscopy. One-way ANOVA and Tukey Tests were used for statistical analysis. Results: The highest amount of antimicrobial activity was found in samples with 3% added CXD. The proportion of viable pathogens were reduced significantly with the addition of 2% and 3 % CXD (P <.05). A noticeable reduction of S. mutans amount was seen with incorporation of 3% CXD (P <.05). S. mutans and C. albicans were inhibited significantly by all the samples when compared to control groups. Conclusions: Addition of 2%-3% CXD to glass ionomer luting cements increased the antimicrobial properties. As, microorganisms’ growth rate was inhibited in 3% CXD group, CXD added glass ionomer luting cement can be suggested in endodontically treated teeth, in high caries-risk patients, also in immunocompromised patients. © 2025, Ataturk Universitesi. All rights reserved.
Açıklama
Anahtar Kelimeler
antibacterial, Antifungal, chlorhexidine diacetate, glass ionomer, luting cements
Kaynak
Current Research in Dental Sciences
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
35
Sayı
4
