Dikkat Eksikliği ve Hiperaktivite Bozukluğu'nda Kan Parametrelerinin İncelenmesi
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Dosyalar
Tarih
2017
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Dikkat eksikliği ve hiperaktivite bozukluğu (DEHB), pediatrik yaş grubunda yaygın olarak görünen nöropsikiyatrik bir bozukluktur. Nedenine yönelik çok sayıda çalışma yapılmış olsa da etiyoloji tam olarak aydınlatılamamıştır. Biz de DEHB tanılı hastalarda bazı kan parametrelerini araştırarak, hastalıkla ilgili literatüre katkı yapmayı amaçladık. Gereç ve Yöntem: Çalışmaya 5-15 yaş arası 91 hasta ve 116 sağlıklı çocuk dahil edildi. Tüm çocuklardan tam kan sayımı, serum demir, total demir bağlama kapasitesi, ferritin, vitamin B12 düzeyi, folik asit düzeyi, serbest T4 ve tiroid stimulan hormon düzeyleri çalışıldı. Bulgular: Hasta grubunun yaş ortalaması 9,02,5 yıl, kontrol grubunun yaş ortalaması 9,73,1 yıl saptandı ve aralarında fark yoktu. Her 2 grupta da erkek cinsiyet oranı yüksekti. Gruplar arasında MCV, RDW, nötrofil sayısı, MPV, trombosit yüzdesi (PCT), trombosit dağılım genişliği (PDW) sonuçları açısından anlamlı değişiklikler saptandı. Serum demir düzeyi kontrol grubunda hasta grubuna göre anlamlı olarak düşüktü. Ferritin değerleri açısından gruplar arasında istatistiksel fark saptanmadı. Vitamin B12, folik asit ve tiroid fonksiyon testleri sonuçları değerlendirildiğinde gruplar arasında istatistiksel olarak anlamlı fark bulunamadı. Sonuç: Gruplar arası anlamlı bulduğumuz sonuçları doğrulamak için daha çok sayıda hasta içeren ileri çalışmalara ihtiyaç vardır.
Objective: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder that is common in the paediatric age group. Although some studies have been conducted on this purpose, the etiology has not been fully elucidated. We aimed to contribute on literature about the disease through investigating some blood parameters at pediatric ADHD patients. Methods: The study included 91 children and 115 healthy children between the ages of 5 and 15 years. Serum iron, total iron binding capacity, ferritin, vitamin B12 level, folic acid level, free T4 and thyroid stimulating hormone levels were studied in whole group. Results: The mean age of the patient group was 9.0 ± 2.5 years, the mean age of the control group was 9.7 ± 3.1 years, and there was no difference between them. Male sex ratio was higher in both groups. Significant changes were detected in MCV, RDW, neutrophil count, MPV, plateletcrit (PCT), platelet distribution width (PDW) results between control and experimental groups. Serum iron level was significantly lower in the control group comparing to the patient group. There was no statistical difference between the groups regarding ferritin values. When the results of vitamin B12, folic acid and thyroid function tests were evaluated, no statistically significant difference was found between the groups. Conclusion: Further studies which involve larger population are essential to confirm the results that our findings to be find meaningful.
Objective: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder that is common in the paediatric age group. Although some studies have been conducted on this purpose, the etiology has not been fully elucidated. We aimed to contribute on literature about the disease through investigating some blood parameters at pediatric ADHD patients. Methods: The study included 91 children and 115 healthy children between the ages of 5 and 15 years. Serum iron, total iron binding capacity, ferritin, vitamin B12 level, folic acid level, free T4 and thyroid stimulating hormone levels were studied in whole group. Results: The mean age of the patient group was 9.0 ± 2.5 years, the mean age of the control group was 9.7 ± 3.1 years, and there was no difference between them. Male sex ratio was higher in both groups. Significant changes were detected in MCV, RDW, neutrophil count, MPV, plateletcrit (PCT), platelet distribution width (PDW) results between control and experimental groups. Serum iron level was significantly lower in the control group comparing to the patient group. There was no statistical difference between the groups regarding ferritin values. When the results of vitamin B12, folic acid and thyroid function tests were evaluated, no statistically significant difference was found between the groups. Conclusion: Further studies which involve larger population are essential to confirm the results that our findings to be find meaningful.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp
Kaynak
Konuralp Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
9
Sayı
3
