Squamous Cell Carcinoma of Bladder

Basit Öğe Kaydı
dc.contributor.authorTaşkıran, Arda Taşkın
dc.contributor.authorBaba, Dursun
dc.date.accessioned2023-07-26T11:57:49Z
dc.date.available2023-07-26T11:57:49Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalıen_US
dc.description.abstractSquamous cell carcinoma (SCC) of the bladder is a malignant neoplasm of a pure squamous phenotype originating from the bladder urothelium. SCC of the bladder is a relatively rare tumor with no specific diagnostic test. The diagnosis is usually made at an advanced stage; therefore, the prognosis is poor and most cases result in mortality. Inflammation and infection leading to the metaplasia of epithelial cells are implicated in its etiology. SCC of the bladder is divided into two groups depending on whether it is due to bilharzial infections, and these two groups have different epidemiological, pathogenetic and clinicopathological features. SCC of the bladder accounts for the vast majority (approximately 75%) of bladder cancers in areas where Schistosoma haematobium infection is endemic. The European Association of Urology guidelines classify bladder cancer with any variant histology as high-risk bladder cancer. Because of the rarity and heterogeneity of non-urothelial tumors, treatments described are mostly based on retrospective series and small studies. Radical cystectomy is recommended as the first treatment in patients presenting with non-metastatic bladder SCC. Neoadjuvant radiation therapy (RT) is considered to play a role in schistosomal bladder cancer. However, there are not enough high-quality studies to indicate the role of RT or chemotherapy as adjuvant therapy. Due to the rarity of the disease, there are also no high-evidence guidelines for managing SCC. There is a need for further high-volume and prospective studies to review literature data and developments.en_US
dc.identifier.doi10.4274/uob.galenos.2021.2021.10.1
dc.identifier.endpage118en_US
dc.identifier.issn2147-2270
dc.identifier.issue4en_US
dc.identifier.startpage113en_US
dc.identifier.urihttps://doi.org/10.4274/uob.galenos.2021.2021.10.1
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13314
dc.identifier.volume21en_US
dc.identifier.wosWOS:000897687700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorTaşkıran, Arda Taşkın
dc.institutionauthorBaba, Dursun
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofUroonkoloji Bulteni-Bulletin of Urooncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectBladder Tumor; Squamous Cell Carcinoma; Urothelial Carcinomaen_US
dc.subjectSpinal-Cord-Injury; Adjuvant Radiation-Therapy; Radical Cystectomy; Urinary-Bladder; Urothelial Carcinoma; Preoperative Irradiation; Histological Variants; Clinical-Significance; Condyloma Acuminatum; Bilharzial Bladderen_US
dc.titleSquamous Cell Carcinoma of Bladderen_US
dc.typeReview Articleen_US

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