Assessment of the neutrophil to lymphocyte ratio in young patients with acute coronary syndromes

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dc.contributor.authorÖztürk, Serkan
dc.contributor.authorErdem, Alim
dc.contributor.authorÖzlü, Mehmet Fatih
dc.contributor.authorAyhan, Selim
dc.contributor.authorErdem, Kemalettin
dc.contributor.authorÖzyaşar, Mehmet
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2020-04-30T13:32:08Z
dc.date.available2020-04-30T13:32:08Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionPubMed ID: 23760114en_US
dc.description.abstractObjectives: It is well known that inflammation plays a key role in both initiation and propagation of acute coronary syndrome (ACS). White blood cell (WBC) and its subtypes are an indicator of inflammation in patients with ACS. We aimed to evaluate the WBC and its subtypes in patients aged <45 year with acute coronary syndromes. Study design: We retrospectively analyzed WBC and its subtypes (including neutrophil and lymphocyte) in 84 patients (<45 year) who were admitted to the emergency department for chest pain suggestive of ACS (44 unstable angina pectoris, 40 non-ST-segment elevation myocardial infarction [NSTEMI]), and 40 healthy controls. Results: Hypertension, diabetes mellitus, smoking, and family history were significantly higher in NSTE-ACS patients. Also, LDL levels was significantly higher and HDL levels was significantly lower in NSTE-ACS patients (p=0.041 and p=0.009). The difference in percent of lymphocytes between the groups was significant (p=0.048). N/L ratio was significantly different between all groups and between the NSTEMI and USAP (p<0.001 and p=0.041). Our results demonstrated that hypertension, percent of neutrophils, and N/L ratio was a significant independent predictor of NSTE-ACS (Beta=0.251, 95% CI=0.002-0.523, p=0.048; beta=0.561, 95% CI=0.008-0.137, p=0.028 and beta=0.260, 95% CI=0.042-0.438, p=0.018, respectively). Conclusion: N/L was found to be elevated in young patients with NSTE-ACS compared with control group. The inflammation assessed using WBC and its subtypes may be more important in young NSTE-ACS patients. © 2013 Turkish Society of Cardiology.en_US
dc.identifier.doi10.5543/tkda.2013.00344en_US
dc.identifier.endpage289en_US
dc.identifier.issn1016-5169
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage284en_US
dc.identifier.urihttps://dx.doi.org/10.5543/tkda.2013.00344
dc.identifier.urihttps://hdl.handle.net/20.500.12684/107
dc.identifier.volume41en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Anaesthesiology and Intensive Care Societyen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute coronary syndrome; Aged; Coronary angiography; Coronary artery disease; Erythrocyte indices; Hemoglobins/metabolism; Inflammation; Leukocytesen_US
dc.titleAssessment of the neutrophil to lymphocyte ratio in young patients with acute coronary syndromesen_US
dc.typeArticleen_US

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