Evaluation of the Relationship between Silent Cerebral Lesions and Triglyceride/HDL-Cholesterol in Patients with First Stroke Attack

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dc.contributor.authorAtasoy, Hüseyın Tugrul
dc.contributor.authorÇelebi, Ulufer
dc.contributor.authorDemirel, Esra Acıman
dc.contributor.authorAcikgoz, Mustafa
dc.contributor.authorKalaycı, Gülcan
dc.contributor.authorÇınar, Bilge Piri
dc.date.accessioned2023-04-10T20:19:38Z
dc.date.available2023-04-10T20:19:38Z
dc.date.issued2020
dc.departmentRektörlük, Rektörlüğe Bağlı Birimler, Düzce Üniversitesi Dergilerien_US
dc.description.abstractim: Triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio is defined as theserum atherogenicity index. High TG/HDL-C ratio is related with vascular diseases, insulinresistance and metabolic syndrome. The TG/HDL-C ratio in cerebrovascular diseases,especially in silent cerebral lesions hasn’t been well studied. The aim of this study was toevaluate the frequency of silent cerebral ischemia (SCI) and leukoaraiosis (LA), and itsrelationship with TG/HDL-C ratio in patients admitted with the first ischemic stroke attack.Material and Methods: We retrospectively evaluated 200 patients who admitted to BulentEcevit University Faculty of Medicine, Department of Neurology with the diagnosis of acutefirst ischemic stroke. Silent cerebral lesions were defined as LA and SCI with magneticresonance imaging. TG/HDL-C ratio was calculated by dividing TG levels by HDL-C levels.Results: Silent cerebral lesions were detected 124 (83.2%) of 149 patients. LA severity wasevaluated according to Fazekas score, 22 (14.8%) of patients were grade 0, 49 (32.9%) of themwere grade 1, and 78 (52.3%) of them were advanced periventricular white matterhyperintensity (adv-PWMH) group. TG/HDL-C ratio in SCI group was higher than the groupwithout SCI, but it wasn’t statistically significant (p=0.091). A significant increase wasobserved in the TG/HDL-C ratio, as LA severity increased. TG/HDL-C ratio was significantlyhigher in adv-PWMH group (p=0.050).Conclusion: High serum atherogenicity index is associated with atherosclerosis and vascularendothelial dysfunction. With this simple, inexpensive and effective test method, high-riskgroup of LA and SCI could be identified.en_US
dc.identifier.doi10.18678/dtfd.737978
dc.identifier.endpage195en_US
dc.identifier.issn1307-671X
dc.identifier.issue3en_US
dc.identifier.startpage191en_US
dc.identifier.trdizinid442622en_US
dc.identifier.urihttp://doi.org/10.18678/dtfd.737978
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/442622
dc.identifier.urihttps://hdl.handle.net/20.500.12684/11450
dc.identifier.volume22en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of the Relationship between Silent Cerebral Lesions and Triglyceride/HDL-Cholesterol in Patients with First Stroke Attacken_US
dc.typeArticleen_US

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