Acromegaly and Pregnancy: Five New Cases

dc.contributor.authorÖnder, Elif
dc.contributor.authorAydın, Yusuf
dc.contributor.authorSoysal, Tuba
dc.contributor.authorTuna, Mazhar
dc.contributor.authorGüngör, Adem
dc.date.accessioned2020-04-30T22:38:57Z
dc.date.available2020-04-30T22:38:57Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000423949600009en_US
dc.description.abstractPregnancy is a rare occurrence in acromegalic patients because of impaired fertility due to the disease. There are limited data available regarding pregnancy in acromegalic patients; although, it appears that the patients are usually able to carry their pregnancies to full term. In addition, certain metabolic effects of acromegaly need to be considered as they can be harmful to both mother and fetus. The discontinuation of the medical treatment is usually recommended as the effects of medical treatment are unclear. Herein, we report five new cases of pregnancies in acromegalic patients who had undergone surgery and medical treatment for macroadenoma, before the onset of pregnancy, from different centers. Two of them had received radiotherapy after the surgery. None of the patients in our study were treated for pregnancy; however, two of them were receiving octreotide when the diagnosis of pregnancy was established. The medical treatment of these two patients was discontinued at the beginning of pregnancy. Four patients delivered healthy babies, and therapeutic abortion was performed at the sixth week of pregnancy to one of the patients who was being treated with octreotide before the pregnancy. Out of the five patients in our study, two had pregestational diabetes and one had hypertension. As a conclusion, it can be said that pregnancy in acromegalic patients is usually uneventful without any treatment throughout the pregnancy.en_US
dc.identifier.doi10.25179/tjem.2017-56497en_US
dc.identifier.endpage139en_US
dc.identifier.issn1301-2193
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage136en_US
dc.identifier.urihttps://doi.org/10.25179/tjem.2017-56497
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2535
dc.identifier.volume21en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurkish Journal Of Endocrinology And Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcromegalyen_US
dc.subjectpregnancyen_US
dc.subjectmedical therapyen_US
dc.titleAcromegaly and Pregnancy: Five New Casesen_US
dc.typeArticleen_US

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