Evaluation of medication adherence and medication beliefs and their relation with quality of life in osteoporotic patients with and without vertebral fractures: a path analysis

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dc.authoridSultanoğlu, Tuba Erdem/0000-0003-0021-5952en_US
dc.authorscopusid57220865918en_US
dc.authorscopusid6601917736en_US
dc.authorwosidSultanoğlu, Tuba Erdem/AAB-1647-2021en_US
dc.contributor.authorSultanoglu, Tuba Erdem
dc.contributor.authorAtaoglu, Safinaz
dc.date.accessioned2024-08-23T16:04:04Z
dc.date.available2024-08-23T16:04:04Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackgroundOsteoporosis (OP) is a public health problem that causes morbidity and mortality with various complications, especially fractures, negatively affects quality of life (QoL) and creates an economic burden on society. The aim of this study was to investigate the relationships among medication adherence, medication beliefs, QoL in Turkish patients with OP.ResultsThe Medication Adherence Report Scale (MARS) total score was 17 in those with vertebral fractures and 18 in those without vertebral fractures. The total Quality of Life Questionnaire of the European Foundation for Osteoporosis (Qualeffo-41) score was 48.7 in those with vertebral fractures and 35.1 in those without vertebral fractures. Visual analog scale (VAS) of pain scores showed a moderate correlation with every domain of the Qualeffo-41 scores (r = 0.401, r = 0.412, r = 0.391, r = 0.402, r = 0.380, r = 0.387 respectively, P = < 0.001). MARS total score, Beliefs about Medicines Questionnaire (BMQ), and Qualeffo-41 parameters were compared between patients with osteoporotic fractures and without fractures. In patients with a vertebral fracture, the patients Qualeffo-41 scores were higher with every domain and their QoL was more impaired (p < 0.001); but there were no significant differences between patients with osteoporotic fractures and without fractures in terms of MARS total score and BMQ domains. The pathway analysis results showed that general beliefs about drugs is associated with the physical function and social function of statistically significant and general overuse is associated with the pain (& beta; = 1.781; p < 0.001), and general health (& beta; = 1,832; p = 0.039). However, self-reported medication adherence and specific beliefs is not associated with the pain, physical function, social function, general health, and mental function (p > 0.05) of statistically significant.ConclusionsEnhancing positive medication beliefs are a promising approach to improve medication adherence, and in turn, improved diseases self management and better QoL, in OP patients.en_US
dc.identifier.doi10.1186/s43166-023-00210-z
dc.identifier.issn1110-161X
dc.identifier.issn2090-3235
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85195538012en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1186/s43166-023-00210-z
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14048
dc.identifier.volume50en_US
dc.identifier.wosWOS:001048338500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.ispartofEgyptian Rheumatology And Rehabilitationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOsteoporosisen_US
dc.subjectVertebrae fractureen_US
dc.subjectMedication adherenceen_US
dc.subjectBeliefs about medicinesen_US
dc.subjectQuality of lifeen_US
dc.subjectEuropean Foundationen_US
dc.subjectRisken_US
dc.subjectQuestionnaireen_US
dc.subjectPersistenceen_US
dc.subjectManagementen_US
dc.titleEvaluation of medication adherence and medication beliefs and their relation with quality of life in osteoporotic patients with and without vertebral fractures: a path analysisen_US
dc.typeArticleen_US

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