Comparison of Hemogram Parameters in Febrile Seizures Types
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Tarih
2020
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info:eu-repo/semantics/openAccess
Özet
Aim: Febrile seizures (FS) are among the most common neurological emergencies duringchildhood and clinically classified into two types, being simple febrile seizures (SFS) andcomplicated febrile seizures (CFS). The differentiation between FS types is important, in thatthey are associated with different morbidity and mortality risks and it is based on the clinicalcharacteristics of each seizure, however there is currently no laboratory test that can guide thisdifferentiation. In this study, the relationship between FS types and hemogram parameters wasevaluated and potential use of these parameters in differential diagnosis was investigated.Material and Methods: This retrospective study included a total of 133 patients whose firstFS met the criteria of an FS, and whose hemogram results were available. The AmericanAcademy of Pediatrics criteria were used to confirm the diagnosis. The patients were dividedinto two groups as SFS and CFS.Results: Hemoglobin (Hb), hematocrit (HCT), mean platelet volume (MPV), neutrophillymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) differed significantly betweentwo groups (p<0.001, p=0.002, p=0.033, p<0.001, p<0.001, respectively), while no significantdifference was identified in total blood count parameters. Moreover, MPV was significantlyhigher in CFS group than in SFS group.Conclusion: This is one of the few studies investigating the potential relationship betweenhemogram parameters and FS types in children. We believe that, although they do not ensurea clear differentiation, Hb, MPV, NLR and PLR may be useful to clinicians in differentiatingbetween FS types, particularly in patients with an unclear seizure history.
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Cilt
22
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1
